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Phenanthroindolizidine alkaloids from the stems of Ficus septica.

Publication ,  Journal Article
Damu, AG; Kuo, PC; Shi, LS; Li, CY; Kuoh, CS; Wu, PL; Wu, TS
Published in: Journal of natural products
July 2005

In addition to six known phenanthroindolizidine alkaloids, eight new alkaloids, namely, ficuseptines B-D (1-3), 10R,13aR-tylophorine N-oxide (4), 10R,13aR-tylocrebrine N-oxide (5), 10S,13aR-tylocrebrine N-oxide (6), 10S,13aR-isotylocrebrine N-oxide (7), and 10S,13aS-isotylocrebrine N-oxide (8), were isolated from a methanol extract of the stems of Ficus septica. The structures of the new compounds were elucidated by means of spectroscopic data interpretation. Cytotoxicity of some of these alkaloids was assessed in vitro using the HONE-1 and NUGC cell lines.

Duke Scholars

Published In

Journal of natural products

ISSN

0163-3864

Publication Date

July 2005

Volume

68

Issue

7

Start / End Page

1071 / 1075

Location

united states

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences
 

Citation

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Damu, A. G., Kuo, P. C., Shi, L. S., Li, C. Y., Kuoh, C. S., Wu, P. L., & Wu, T. S. (2005). Phenanthroindolizidine alkaloids from the stems of Ficus septica. Journal of Natural Products, 68(7), 1071–1075.
Damu, A. G., P. C. Kuo, L. S. Shi, C. Y. Li, C. S. Kuoh, P. L. Wu, and T. S. Wu. “Phenanthroindolizidine alkaloids from the stems of Ficus septica.Journal of Natural Products 68, no. 7 (July 2005): 1071–75.
Damu AG, Kuo PC, Shi LS, Li CY, Kuoh CS, Wu PL, et al. Phenanthroindolizidine alkaloids from the stems of Ficus septica. Journal of natural products. 2005 Jul;68(7):1071–5.
Damu, A. G., et al. “Phenanthroindolizidine alkaloids from the stems of Ficus septica.Journal of Natural Products, vol. 68, no. 7, July 2005, pp. 1071–75.
Damu AG, Kuo PC, Shi LS, Li CY, Kuoh CS, Wu PL, Wu TS. Phenanthroindolizidine alkaloids from the stems of Ficus septica. Journal of natural products. 2005 Jul;68(7):1071–1075.
Journal cover image

Published In

Journal of natural products

ISSN

0163-3864

Publication Date

July 2005

Volume

68

Issue

7

Start / End Page

1071 / 1075

Location

united states

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences