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Candida mediastinitis after a cardiac operation.

Publication ,  Journal Article
Glower, DD; Douglas, JM; Gaynor, JW; Jones, RN; Oldham, HN
Published in: Ann Thorac Surg
January 1990

Candida mediastinitis is a rare condition characterized by a high mortality and chronic morbidity, Including the present review, only 39 cases have been described, 67% occurring after a cardiac operation. Candida mediastinitis has a 55% mortality in the postoperative setting and a mortality of 92% among patients without a prior cardiac procedure. Although no patient survived Candida mediastinitis without surgical drainage of the mediastinum, survival was 85% among 13 patients who underwent operative mediastinal drainage. Chronic wound infection developed in 6 survivors of operative drainage without muscle flap closure, but in all patients closed with vascularized flaps, healing ultimately occurred. Aggressive surgical management with mediastinal drainage, sternal debridement, and early wound closure with vascularized flaps are essential to minimize the otherwise high morbidity and mortality of Candida mediastinitis.

Duke Scholars

Published In

Ann Thorac Surg

DOI

ISSN

0003-4975

Publication Date

January 1990

Volume

49

Issue

1

Start / End Page

157 / 163

Location

Netherlands

Related Subject Headings

  • Respiratory System
  • Pericarditis
  • Pericardial Effusion
  • Middle Aged
  • Mediastinitis
  • Male
  • Humans
  • Diabetes Mellitus, Type 1
  • Coronary Artery Bypass
  • Candidiasis
 

Citation

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Glower, D. D., Douglas, J. M., Gaynor, J. W., Jones, R. N., & Oldham, H. N. (1990). Candida mediastinitis after a cardiac operation. Ann Thorac Surg, 49(1), 157–163. https://doi.org/10.1016/0003-4975(90)90382-g
Glower, D. D., J. M. Douglas, J. W. Gaynor, R. N. Jones, and H. N. Oldham. “Candida mediastinitis after a cardiac operation.Ann Thorac Surg 49, no. 1 (January 1990): 157–63. https://doi.org/10.1016/0003-4975(90)90382-g.
Glower DD, Douglas JM, Gaynor JW, Jones RN, Oldham HN. Candida mediastinitis after a cardiac operation. Ann Thorac Surg. 1990 Jan;49(1):157–63.
Glower, D. D., et al. “Candida mediastinitis after a cardiac operation.Ann Thorac Surg, vol. 49, no. 1, Jan. 1990, pp. 157–63. Pubmed, doi:10.1016/0003-4975(90)90382-g.
Glower DD, Douglas JM, Gaynor JW, Jones RN, Oldham HN. Candida mediastinitis after a cardiac operation. Ann Thorac Surg. 1990 Jan;49(1):157–163.
Journal cover image

Published In

Ann Thorac Surg

DOI

ISSN

0003-4975

Publication Date

January 1990

Volume

49

Issue

1

Start / End Page

157 / 163

Location

Netherlands

Related Subject Headings

  • Respiratory System
  • Pericarditis
  • Pericardial Effusion
  • Middle Aged
  • Mediastinitis
  • Male
  • Humans
  • Diabetes Mellitus, Type 1
  • Coronary Artery Bypass
  • Candidiasis