Skip to main content
Journal cover image

Micro-anastomosis of 0.3-0.4 mm vessels after cold ischemia using a rat model of toe-to-thumb transplantation.

Publication ,  Journal Article
Chaopricha, W; Chen, LE; Seaber, AV; Bossen, E; Urbaniak, JR
Published in: Microsurgery
1993

Anastomoses of vessels of less than 0.5 mm in diameter remain a challenge from the technical aspect. Clinically such anastomoses are necessary for replantation of the distal digit in adults and whole digits in children. Survival data for replantation of these parts after prolonged ischemia have not yet been reported. Since a rat foot has an anatomic structure similar to the human hand, we used 40 rats as models of toe-to-thumb transplantation to study the survival rates of transplanted toes after various periods of cold ischemia (4 degrees C) of the amputated part. While a 100% success rate was achieved following immediate transplantation of the amputated digits (control group), the survival rates were 87.5, 75, 75, and 62.5% after transplantation of digits cooled for 24, 48, 72, and 96 hours, respectively (groups 2-5). No exact ischemic time limit was demonstrated. The results suggest that, in this model, optimal digital replantation results are achievable even after a 24 hour period of cooling preservation.

Duke Scholars

Published In

Microsurgery

DOI

ISSN

0738-1085

Publication Date

1993

Volume

14

Issue

9

Start / End Page

619 / 623

Location

United States

Related Subject Headings

  • Vascular Patency
  • Toes
  • Thumb
  • Surgery
  • Rats, Sprague-Dawley
  • Rats
  • Organ Preservation
  • Microsurgery
  • Male
  • Hindlimb
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chaopricha, W., Chen, L. E., Seaber, A. V., Bossen, E., & Urbaniak, J. R. (1993). Micro-anastomosis of 0.3-0.4 mm vessels after cold ischemia using a rat model of toe-to-thumb transplantation. Microsurgery, 14(9), 619–623. https://doi.org/10.1002/micr.1920140915
Chaopricha, W., L. E. Chen, A. V. Seaber, E. Bossen, and J. R. Urbaniak. “Micro-anastomosis of 0.3-0.4 mm vessels after cold ischemia using a rat model of toe-to-thumb transplantation.Microsurgery 14, no. 9 (1993): 619–23. https://doi.org/10.1002/micr.1920140915.
Chaopricha W, Chen LE, Seaber AV, Bossen E, Urbaniak JR. Micro-anastomosis of 0.3-0.4 mm vessels after cold ischemia using a rat model of toe-to-thumb transplantation. Microsurgery. 1993;14(9):619–23.
Chaopricha, W., et al. “Micro-anastomosis of 0.3-0.4 mm vessels after cold ischemia using a rat model of toe-to-thumb transplantation.Microsurgery, vol. 14, no. 9, 1993, pp. 619–23. Pubmed, doi:10.1002/micr.1920140915.
Chaopricha W, Chen LE, Seaber AV, Bossen E, Urbaniak JR. Micro-anastomosis of 0.3-0.4 mm vessels after cold ischemia using a rat model of toe-to-thumb transplantation. Microsurgery. 1993;14(9):619–623.
Journal cover image

Published In

Microsurgery

DOI

ISSN

0738-1085

Publication Date

1993

Volume

14

Issue

9

Start / End Page

619 / 623

Location

United States

Related Subject Headings

  • Vascular Patency
  • Toes
  • Thumb
  • Surgery
  • Rats, Sprague-Dawley
  • Rats
  • Organ Preservation
  • Microsurgery
  • Male
  • Hindlimb