Glucocorticosteroid inhibition of intraocular proliferation after injury.
Publication
, Journal Article
Tano, Y; Chandler, DB; McCuen, BW; Machemer, R
Published in: Am J Ophthalmol
February 1981
Perforating injuries were produced in the posterior segment of rabbit eyes. We studied the inhibitory effect of a slowly water-soluble corticosteroid, dexamethasone alcohol, on fibroblast growth. The treated group received a single intravitreal injection of 1 mg of the corticosteroid. The eyes were observed for four weeks. Transvitreal proliferation was significantly decreased and wound healing was delayed as compared to a control group. Inhibition of intraocular proliferation by high doses of intravitreally injected corticosteroid may be useful in the treatment of eyes with penetrating and perforating injuries.
Duke Scholars
Published In
Am J Ophthalmol
DOI
ISSN
0002-9394
Publication Date
February 1981
Volume
91
Issue
2
Start / End Page
184 / 189
Location
United States
Related Subject Headings
- Wound Healing
- Rabbits
- Ophthalmology & Optometry
- Fibroblasts
- Female
- Eye Injuries
- Dexamethasone
- Animals
- 3212 Ophthalmology and optometry
- 1117 Public Health and Health Services
Citation
APA
Chicago
ICMJE
MLA
NLM
Tano, Y., Chandler, D. B., McCuen, B. W., & Machemer, R. (1981). Glucocorticosteroid inhibition of intraocular proliferation after injury. Am J Ophthalmol, 91(2), 184–189. https://doi.org/10.1016/0002-9394(81)90171-9
Tano, Y., D. B. Chandler, B. W. McCuen, and R. Machemer. “Glucocorticosteroid inhibition of intraocular proliferation after injury.” Am J Ophthalmol 91, no. 2 (February 1981): 184–89. https://doi.org/10.1016/0002-9394(81)90171-9.
Tano Y, Chandler DB, McCuen BW, Machemer R. Glucocorticosteroid inhibition of intraocular proliferation after injury. Am J Ophthalmol. 1981 Feb;91(2):184–9.
Tano, Y., et al. “Glucocorticosteroid inhibition of intraocular proliferation after injury.” Am J Ophthalmol, vol. 91, no. 2, Feb. 1981, pp. 184–89. Pubmed, doi:10.1016/0002-9394(81)90171-9.
Tano Y, Chandler DB, McCuen BW, Machemer R. Glucocorticosteroid inhibition of intraocular proliferation after injury. Am J Ophthalmol. 1981 Feb;91(2):184–189.
Published In
Am J Ophthalmol
DOI
ISSN
0002-9394
Publication Date
February 1981
Volume
91
Issue
2
Start / End Page
184 / 189
Location
United States
Related Subject Headings
- Wound Healing
- Rabbits
- Ophthalmology & Optometry
- Fibroblasts
- Female
- Eye Injuries
- Dexamethasone
- Animals
- 3212 Ophthalmology and optometry
- 1117 Public Health and Health Services