
Reduction in the minimum candidate interval in the dominant-intermediate form of Charcot-Marie-Tooth neuropathy to D19S586 to D19S432.
Publication
, Journal Article
Speer, MC; Graham, FL; Bonner, E; Collier, K; Stajich, JM; Gaskell, PC; Pericak-Vance, MA; Vance, JM
Published in: Neurogenetics
October 2002
As part of an on-going genomic screen of unlinked Charcot-Marie-Tooth disease type 2 (CMT2) families, we identified 11 regions in the genome with lod scores > or = 1.0. One of these regions was near the recently identified CMTDI1 locus on 19q. We show evidence of linkage of DUK 1118 to this region and our data reduce the minimum candidate interval for CMTDI1 to the 9-cM interval spanned by D19S586 and D19S432. We also demonstrate that five additional CMT2 families are unlinked to 19q markers, providing further evidence of CMT2 heterogeneity.
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Published In
Neurogenetics
DOI
ISSN
1364-6745
Publication Date
October 2002
Volume
4
Issue
2
Start / End Page
83 / 85
Location
United States
Related Subject Headings
- Pedigree
- Neurology & Neurosurgery
- Male
- Lod Score
- Humans
- Genetic Markers
- Genetic Heterogeneity
- Genes, Dominant
- Female
- Charcot-Marie-Tooth Disease
Citation
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ICMJE
MLA
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Speer, M. C., Graham, F. L., Bonner, E., Collier, K., Stajich, J. M., Gaskell, P. C., … Vance, J. M. (2002). Reduction in the minimum candidate interval in the dominant-intermediate form of Charcot-Marie-Tooth neuropathy to D19S586 to D19S432. Neurogenetics, 4(2), 83–85. https://doi.org/10.1007/s10048-002-0139-3
Speer, Marcy C., Felicia Lennon Graham, Erin Bonner, Keva Collier, Jeffrey M. Stajich, Perry C. Gaskell, Margaret A. Pericak-Vance, and Jeffery M. Vance. “Reduction in the minimum candidate interval in the dominant-intermediate form of Charcot-Marie-Tooth neuropathy to D19S586 to D19S432.” Neurogenetics 4, no. 2 (October 2002): 83–85. https://doi.org/10.1007/s10048-002-0139-3.
Speer MC, Graham FL, Bonner E, Collier K, Stajich JM, Gaskell PC, et al. Reduction in the minimum candidate interval in the dominant-intermediate form of Charcot-Marie-Tooth neuropathy to D19S586 to D19S432. Neurogenetics. 2002 Oct;4(2):83–5.
Speer, Marcy C., et al. “Reduction in the minimum candidate interval in the dominant-intermediate form of Charcot-Marie-Tooth neuropathy to D19S586 to D19S432.” Neurogenetics, vol. 4, no. 2, Oct. 2002, pp. 83–85. Pubmed, doi:10.1007/s10048-002-0139-3.
Speer MC, Graham FL, Bonner E, Collier K, Stajich JM, Gaskell PC, Pericak-Vance MA, Vance JM. Reduction in the minimum candidate interval in the dominant-intermediate form of Charcot-Marie-Tooth neuropathy to D19S586 to D19S432. Neurogenetics. 2002 Oct;4(2):83–85.

Published In
Neurogenetics
DOI
ISSN
1364-6745
Publication Date
October 2002
Volume
4
Issue
2
Start / End Page
83 / 85
Location
United States
Related Subject Headings
- Pedigree
- Neurology & Neurosurgery
- Male
- Lod Score
- Humans
- Genetic Markers
- Genetic Heterogeneity
- Genes, Dominant
- Female
- Charcot-Marie-Tooth Disease