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Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients.

Publication ,  Journal Article
Mahaley, MS; Brooks, WH; Roszman, TL; Bigner, DD; Dudka, L; Richardson, S
Published in: J Neurosurg
April 1977

Cellular and humoral immune parameters were evaluated in a series of brain-tumor patients, 42 with glioblastoma multiforme, 17 with other anaplastic gliomas, and 17 with meningiomas. A degree of anergy was found, which seems in the group as a whole to be proportional to the degree of anaplasia. In addition, serial bimonthyl testing in individual cases revealed further reduction in certain immune responses coincident with clinical decline.

Duke Scholars

Published In

J Neurosurg

DOI

ISSN

0022-3085

Publication Date

April 1977

Volume

46

Issue

4

Start / End Page

467 / 476

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Meningioma
  • Immunoglobulin M
  • Immunoglobulin G
  • Immunoglobulin A
  • Immunity, Cellular
  • Immunity
  • Hypersensitivity, Delayed
  • Humans
  • Glioma
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Mahaley, M. S., Brooks, W. H., Roszman, T. L., Bigner, D. D., Dudka, L., & Richardson, S. (1977). Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients. J Neurosurg, 46(4), 467–476. https://doi.org/10.3171/jns.1977.46.4.0467
Mahaley, M. S., W. H. Brooks, T. L. Roszman, D. D. Bigner, L. Dudka, and S. Richardson. “Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients.J Neurosurg 46, no. 4 (April 1977): 467–76. https://doi.org/10.3171/jns.1977.46.4.0467.
Mahaley MS, Brooks WH, Roszman TL, Bigner DD, Dudka L, Richardson S. Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients. J Neurosurg. 1977 Apr;46(4):467–76.
Mahaley, M. S., et al. “Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients.J Neurosurg, vol. 46, no. 4, Apr. 1977, pp. 467–76. Pubmed, doi:10.3171/jns.1977.46.4.0467.
Mahaley MS, Brooks WH, Roszman TL, Bigner DD, Dudka L, Richardson S. Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients. J Neurosurg. 1977 Apr;46(4):467–476.

Published In

J Neurosurg

DOI

ISSN

0022-3085

Publication Date

April 1977

Volume

46

Issue

4

Start / End Page

467 / 476

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Meningioma
  • Immunoglobulin M
  • Immunoglobulin G
  • Immunoglobulin A
  • Immunity, Cellular
  • Immunity
  • Hypersensitivity, Delayed
  • Humans
  • Glioma