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The lens epithelium contains glial fibrillary acidic protein (GFAP).

Publication ,  Journal Article
Hatfield, JS; Skoff, RP; Maisel, H; Eng, L; Bigner, DD
Published in: J Neuroimmunol
June 1985

Both polyclonal and monoclonal antibodies to glial fibrillary acidic protein (GFAP) intensely immunostain the lens epithelium. Two-dimensional gels of mouse lens epithelium protein extracts reveal a protein which co-migrates with GFAP from spinal cord. A lens epithelial protein of approximately 50 000 MW on one-dimensional gels is immunoreactive with antiserum to GFAP (Hatfield et al. 1984). GFAP has been regarded as a protein unique to neuroglial cells but this study indicates that some cells of ectodermal origin (the lens epithelium) express GFAP.

Duke Scholars

Published In

J Neuroimmunol

DOI

ISSN

0165-5728

Publication Date

June 1985

Volume

8

Issue

4-6

Start / End Page

347 / 357

Location

Netherlands

Related Subject Headings

  • Neurology & Neurosurgery
  • Mice
  • Lens, Crystalline
  • Immunoenzyme Techniques
  • Histocytochemistry
  • Glial Fibrillary Acidic Protein
  • Fluorescent Antibody Technique
  • Epithelium
  • Electrophoresis
  • Brain Chemistry
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hatfield, J. S., Skoff, R. P., Maisel, H., Eng, L., & Bigner, D. D. (1985). The lens epithelium contains glial fibrillary acidic protein (GFAP). J Neuroimmunol, 8(4–6), 347–357. https://doi.org/10.1016/s0165-5728(85)80072-2
Hatfield, J. S., R. P. Skoff, H. Maisel, L. Eng, and D. D. Bigner. “The lens epithelium contains glial fibrillary acidic protein (GFAP).J Neuroimmunol 8, no. 4–6 (June 1985): 347–57. https://doi.org/10.1016/s0165-5728(85)80072-2.
Hatfield JS, Skoff RP, Maisel H, Eng L, Bigner DD. The lens epithelium contains glial fibrillary acidic protein (GFAP). J Neuroimmunol. 1985 Jun;8(4–6):347–57.
Hatfield, J. S., et al. “The lens epithelium contains glial fibrillary acidic protein (GFAP).J Neuroimmunol, vol. 8, no. 4–6, June 1985, pp. 347–57. Pubmed, doi:10.1016/s0165-5728(85)80072-2.
Hatfield JS, Skoff RP, Maisel H, Eng L, Bigner DD. The lens epithelium contains glial fibrillary acidic protein (GFAP). J Neuroimmunol. 1985 Jun;8(4–6):347–357.
Journal cover image

Published In

J Neuroimmunol

DOI

ISSN

0165-5728

Publication Date

June 1985

Volume

8

Issue

4-6

Start / End Page

347 / 357

Location

Netherlands

Related Subject Headings

  • Neurology & Neurosurgery
  • Mice
  • Lens, Crystalline
  • Immunoenzyme Techniques
  • Histocytochemistry
  • Glial Fibrillary Acidic Protein
  • Fluorescent Antibody Technique
  • Epithelium
  • Electrophoresis
  • Brain Chemistry