Skip to main content

Proteomics in prostate cancer.

Publication ,  Journal Article
Bañez, LL; Srivastava, S; Moul, JW
Published in: Curr Opin Urol
May 2005

PURPOSE OF REVIEW: State-of-the-art proteomics technologies are currently being assessed for utility in the study of prostatic malignancy. This review aims to provide background information on the current proteomics techniques employed in prostate cancer research, recent reports showing the potential application of proteomics in urological practice, and the future direction of proteomics in prostate cancer research and management. RECENT FINDINGS: Proteomic profiling of serum as a diagnostic tool and a platform for biomarker discovery in prostate cancer continues to draw favorable attention as well as close scrutiny as technological enhancements and multi-center study results are reported. In-vitro studies on prostate cell lines provide positive proof-of-principle results. The application of proteomics to query prostate tissue specimens yields novel prostate cancer biomarkers requiring further validation. The integration of proteomics with immunology also yields promising findings that may translate into clinically relevant biological assays. SUMMARY: The study of proteomics is an emerging research field, and current studies continue to display potential future usage in prostate cancer management. Succeeding scientific investigations will probably yield new diagnostic and prognostic tools for prostate cancer, provide insights into its underlying biology, and contribute to the development of novel treatment strategies.

Duke Scholars

Published In

Curr Opin Urol

DOI

ISSN

0963-0643

Publication Date

May 2005

Volume

15

Issue

3

Start / End Page

151 / 156

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Semen
  • Proteomics
  • Prostatic Neoplasms
  • Neoplasm Proteins
  • Mass Spectrometry
  • Male
  • Isotope Labeling
  • Humans
  • Gene Expression
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bañez, L. L., Srivastava, S., & Moul, J. W. (2005). Proteomics in prostate cancer. Curr Opin Urol, 15(3), 151–156. https://doi.org/10.1097/01.mou.0000165547.48922.12
Bañez, Lionel L., Shiv Srivastava, and Judd W. Moul. “Proteomics in prostate cancer.Curr Opin Urol 15, no. 3 (May 2005): 151–56. https://doi.org/10.1097/01.mou.0000165547.48922.12.
Bañez LL, Srivastava S, Moul JW. Proteomics in prostate cancer. Curr Opin Urol. 2005 May;15(3):151–6.
Bañez, Lionel L., et al. “Proteomics in prostate cancer.Curr Opin Urol, vol. 15, no. 3, May 2005, pp. 151–56. Pubmed, doi:10.1097/01.mou.0000165547.48922.12.
Bañez LL, Srivastava S, Moul JW. Proteomics in prostate cancer. Curr Opin Urol. 2005 May;15(3):151–156.

Published In

Curr Opin Urol

DOI

ISSN

0963-0643

Publication Date

May 2005

Volume

15

Issue

3

Start / End Page

151 / 156

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Semen
  • Proteomics
  • Prostatic Neoplasms
  • Neoplasm Proteins
  • Mass Spectrometry
  • Male
  • Isotope Labeling
  • Humans
  • Gene Expression