Scholars@Duke publication: Surface-enhanced Raman analysis of benzo[a]pyrene-DNA adducts on silver-coated cellulose substrates

Surface-enhanced Raman analysis of benzo[a]pyrene-DNA adducts on silver-coated cellulose substrates

Publication , Journal Article

Vo Dinh, T; Uziel, M; Morrison, AL

Published in: Appl. Spectrosc. (USA)

1987

Benzo[a]pyrene-7,8-diol-9,10 epoxide (BPDE)-DNA adducts have been analyzed by surface-enhanced Raman scattering (SERS) spectrometry. BPDE is the ultimate carcinogenic metabolite of benzo[a]pyrene. The SERS measurements were performed with the use of a silver-coated cellulose material at the SERS-active substrate. The acid hydrolyzed products of BPDE-DNA adducts, DNA, and the BP-tetrols were also analyzed by SERS. The results indicate that SERS has great promise as a tool for detecting BPDE-DNA adducts in biological samples

Duke Scholars

Author Tuan Vo-Dinh Biomedical Engineering

Published In

Appl. Spectrosc. (USA)

Publication Date

1987

Volume

Issue

Start / End Page

605 / 610

Related Subject Headings

Analytical Chemistry
0913 Mechanical Engineering
0306 Physical Chemistry (incl. Structural)
0301 Analytical Chemistry

Citation

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Vo Dinh, T., Uziel, M., & Morrison, A. L. (1987). Surface-enhanced Raman analysis of benzo[a]pyrene-DNA adducts on silver-coated cellulose substrates. Appl. Spectrosc. (USA), 41(4), 605–610.

Vo Dinh, T., M. Uziel, and A. L. Morrison. “Surface-enhanced Raman analysis of benzo[a]pyrene-DNA adducts on silver-coated cellulose substrates.” Appl. Spectrosc. (USA) 41, no. 4 (1987): 605–10.

Vo Dinh T, Uziel M, Morrison AL. Surface-enhanced Raman analysis of benzo[a]pyrene-DNA adducts on silver-coated cellulose substrates. Appl Spectrosc (USA). 1987;41(4):605–10.

Vo Dinh, T., et al. “Surface-enhanced Raman analysis of benzo[a]pyrene-DNA adducts on silver-coated cellulose substrates.” Appl. Spectrosc. (USA), vol. 41, no. 4, 1987, pp. 605–10.

Vo Dinh T, Uziel M, Morrison AL. Surface-enhanced Raman analysis of benzo[a]pyrene-DNA adducts on silver-coated cellulose substrates. Appl Spectrosc (USA). 1987;41(4):605–610.