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Antibody-based biosensor for breast cancer with ultrasonic regeneration.

Publication ,  Journal Article
Moreno-Bondi, MC; Mobley, J; Alarie, JP; Vo-Dinh, T
Published in: Journal of biomedical optics
July 2000

We describe a novel method and instrumental setup for regenerating antibodies immobilized on a fiberoptic probe of an immunosensor using ultrasonic irradiation with broadband imaging transducers. The instrumental setup and irradiation conditions for antibody regeneration using ultrasound are described. The results of the measurements with antibody against breast cancer antigen illustrate the effectiveness and potential of the regenerable immunosensor. A 65% removal of the antigens bound to the Mab immobilized on the fiber surface is attained after ultrasound regeneration.

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Published In

Journal of biomedical optics

DOI

EISSN

1560-2281

ISSN

1083-3668

Publication Date

July 2000

Volume

5

Issue

3

Start / End Page

350 / 354

Related Subject Headings

  • Ultrasonography
  • Reproducibility of Results
  • Optics
  • Humans
  • Fiber Optic Technology
  • Female
  • Breast Neoplasms
  • Biosensing Techniques
  • Antibodies, Neoplasm
  • Antibodies, Monoclonal
 

Citation

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Moreno-Bondi, M. C., Mobley, J., Alarie, J. P., & Vo-Dinh, T. (2000). Antibody-based biosensor for breast cancer with ultrasonic regeneration. Journal of Biomedical Optics, 5(3), 350–354. https://doi.org/10.1117/1.430006
Moreno-Bondi, M. C., J. Mobley, J. P. Alarie, and T. Vo-Dinh. “Antibody-based biosensor for breast cancer with ultrasonic regeneration.Journal of Biomedical Optics 5, no. 3 (July 2000): 350–54. https://doi.org/10.1117/1.430006.
Moreno-Bondi MC, Mobley J, Alarie JP, Vo-Dinh T. Antibody-based biosensor for breast cancer with ultrasonic regeneration. Journal of biomedical optics. 2000 Jul;5(3):350–4.
Moreno-Bondi, M. C., et al. “Antibody-based biosensor for breast cancer with ultrasonic regeneration.Journal of Biomedical Optics, vol. 5, no. 3, July 2000, pp. 350–54. Epmc, doi:10.1117/1.430006.
Moreno-Bondi MC, Mobley J, Alarie JP, Vo-Dinh T. Antibody-based biosensor for breast cancer with ultrasonic regeneration. Journal of biomedical optics. 2000 Jul;5(3):350–354.

Published In

Journal of biomedical optics

DOI

EISSN

1560-2281

ISSN

1083-3668

Publication Date

July 2000

Volume

5

Issue

3

Start / End Page

350 / 354

Related Subject Headings

  • Ultrasonography
  • Reproducibility of Results
  • Optics
  • Humans
  • Fiber Optic Technology
  • Female
  • Breast Neoplasms
  • Biosensing Techniques
  • Antibodies, Neoplasm
  • Antibodies, Monoclonal