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Hyperemesis gravidarum complicated by Wernicke's encephalopathy.

Publication ,  Journal Article
Spruill, SC; Kuller, JA
Published in: Obstet Gynecol
May 2002

BACKGROUND: Wernicke's encephalopathy is usually associated with alcohol abuse, but can also occur with hyperemesis gravidarum. The effect of delay in thiamine replacement on fetal outcomes is unknown. We present a case of this complication. CASE: A primipara with hyperemesis was admitted for mental status changes in her 14th week of pregnancy. Physical examination revealed a lethargic patient with ophthalmoplegia, ataxia, and hyporeflexia. Parenteral thiamine therapy was started. The patient improved rapidly although the ataxia persisted. A spontaneous abortion occurred 2 weeks later. CONCLUSION: Wernicke's encephalopathy can complicate hyperemesis gravidarum. Early thiamine replacement may decrease the chances of spontaneous abortion.

Duke Scholars

Published In

Obstet Gynecol

DOI

ISSN

0029-7844

Publication Date

May 2002

Volume

99

Issue

5 Pt 2

Start / End Page

875 / 877

Location

United States

Related Subject Headings

  • Wernicke Encephalopathy
  • Thiamine
  • Pregnancy Trimester, First
  • Pregnancy Complications
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Hyperemesis Gravidarum
  • Humans
  • Female
  • Abortion, Spontaneous
 

Citation

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ICMJE
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Spruill, S. C., & Kuller, J. A. (2002). Hyperemesis gravidarum complicated by Wernicke's encephalopathy. Obstet Gynecol, 99(5 Pt 2), 875–877. https://doi.org/10.1016/s0029-7844(01)01603-9
Spruill, Steven C., and Jeffrey A. Kuller. “Hyperemesis gravidarum complicated by Wernicke's encephalopathy.Obstet Gynecol 99, no. 5 Pt 2 (May 2002): 875–77. https://doi.org/10.1016/s0029-7844(01)01603-9.
Spruill SC, Kuller JA. Hyperemesis gravidarum complicated by Wernicke's encephalopathy. Obstet Gynecol. 2002 May;99(5 Pt 2):875–7.
Spruill, Steven C., and Jeffrey A. Kuller. “Hyperemesis gravidarum complicated by Wernicke's encephalopathy.Obstet Gynecol, vol. 99, no. 5 Pt 2, May 2002, pp. 875–77. Pubmed, doi:10.1016/s0029-7844(01)01603-9.
Spruill SC, Kuller JA. Hyperemesis gravidarum complicated by Wernicke's encephalopathy. Obstet Gynecol. 2002 May;99(5 Pt 2):875–877.
Journal cover image

Published In

Obstet Gynecol

DOI

ISSN

0029-7844

Publication Date

May 2002

Volume

99

Issue

5 Pt 2

Start / End Page

875 / 877

Location

United States

Related Subject Headings

  • Wernicke Encephalopathy
  • Thiamine
  • Pregnancy Trimester, First
  • Pregnancy Complications
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Hyperemesis Gravidarum
  • Humans
  • Female
  • Abortion, Spontaneous