An artificial neural network for lesion detection on single-photon emission computed tomographic images.
RATIONALE AND OBJECTIVES: An artificial neural network (ANN) has been developed to detect nonactive circular lesions on single-slice, single-photon emission computed tomographic (SPECT) images reconstructed using filtered back projection (FBP). METHODS: The neural network is a single-layer perception which learns to identify features on the SPECT image using supervised training with a modified delta rule. The network was trained on a set of SPECT images containing clinically realistic levels of noise. The trained network was applied to a set of 120 images, and the detection performance was evaluated at several decision thresholds using receiver operating characteristic (ROC) analysis. RESULTS: The trained neural network performed better than human observers for the same detection task with the same images as reflected by a significantly larger ROC curve area. CONCLUSIONS: ANN can be trained successfully to perform lesion detection on reconstructed SPECT images.
Duke Scholars
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Related Subject Headings
- Tomography, Emission-Computed, Single-Photon
- Software Design
- ROC Curve
- Observer Variation
- Nuclear Medicine & Medical Imaging
- Neural Networks, Computer
- Models, Structural
- Humans
- Equipment Design
- 3202 Clinical sciences
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Tomography, Emission-Computed, Single-Photon
- Software Design
- ROC Curve
- Observer Variation
- Nuclear Medicine & Medical Imaging
- Neural Networks, Computer
- Models, Structural
- Humans
- Equipment Design
- 3202 Clinical sciences