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Intrauterine diethylstilbestrol exposure and its consequences: pathologic characteristics of vaginal adenosis, clear cell adenocarcinoma, and related lesions.

Publication ,  Journal Article
Robboy, SJ; Scully, RE; Welch, WR; Herbst, AL
Published in: Arch Pathol Lab Med
January 1977

In 1971, the development of clear cell adenocarcinoma of the vagina in young females was first linked to a history of intrauterine exposure to diethylstilbestrol (DES). This communication reviews data on cases accessioned in the Registry of Clear Cell Adenocarcinoma of the Genital Tract in Young Females, findings in exposed female and male subjects without cancer, and discusses current concepts of the pathogenesis of the DES-related anomalies of the lower genital tract.

Duke Scholars

Published In

Arch Pathol Lab Med

ISSN

0003-9985

Publication Date

January 1977

Volume

101

Issue

1

Start / End Page

1 / 5

Location

United States

Related Subject Headings

  • Vaginal Neoplasms
  • Vaginal Diseases
  • Uterine Cervical Diseases
  • Pathology
  • Neoplasm Metastasis
  • Metaplasia
  • Male
  • Humans
  • Female
  • Epithelium
 

Citation

Published In

Arch Pathol Lab Med

ISSN

0003-9985

Publication Date

January 1977

Volume

101

Issue

1

Start / End Page

1 / 5

Location

United States

Related Subject Headings

  • Vaginal Neoplasms
  • Vaginal Diseases
  • Uterine Cervical Diseases
  • Pathology
  • Neoplasm Metastasis
  • Metaplasia
  • Male
  • Humans
  • Female
  • Epithelium