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On the assessment of similarity for dissolution profiles of two drug products.

Publication ,  Journal Article
Chow, S-C; Shao, J
Published in: J Biopharm Stat
August 2002

The assessment of similarity between dissolution profiles of two drug products is considered. After reviewing some existing approaches, we propose a statistical method of assessing local and global similarities based on a time series model for the ratio of the dissolution results from two drug products and a polynominal model for the mean of the ratio. An example is presented for illustration.

Duke Scholars

Published In

J Biopharm Stat

DOI

ISSN

1054-3406

Publication Date

August 2002

Volume

12

Issue

3

Start / End Page

311 / 321

Location

England

Related Subject Headings

  • Statistics & Probability
  • Solubility
  • Pharmaceutical Preparations
  • Models, Statistical
  • Kinetics
  • Algorithms
  • 4905 Statistics
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chow, S.-C., & Shao, J. (2002). On the assessment of similarity for dissolution profiles of two drug products. J Biopharm Stat, 12(3), 311–321. https://doi.org/10.1081/bip-120014561
Chow, Shein-Chung, and Jun Shao. “On the assessment of similarity for dissolution profiles of two drug products.J Biopharm Stat 12, no. 3 (August 2002): 311–21. https://doi.org/10.1081/bip-120014561.
Chow S-C, Shao J. On the assessment of similarity for dissolution profiles of two drug products. J Biopharm Stat. 2002 Aug;12(3):311–21.
Chow, Shein-Chung, and Jun Shao. “On the assessment of similarity for dissolution profiles of two drug products.J Biopharm Stat, vol. 12, no. 3, Aug. 2002, pp. 311–21. Pubmed, doi:10.1081/bip-120014561.
Chow S-C, Shao J. On the assessment of similarity for dissolution profiles of two drug products. J Biopharm Stat. 2002 Aug;12(3):311–321.
Journal cover image

Published In

J Biopharm Stat

DOI

ISSN

1054-3406

Publication Date

August 2002

Volume

12

Issue

3

Start / End Page

311 / 321

Location

England

Related Subject Headings

  • Statistics & Probability
  • Solubility
  • Pharmaceutical Preparations
  • Models, Statistical
  • Kinetics
  • Algorithms
  • 4905 Statistics
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences