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Immunization and the American way: 4 childhood vaccines.

Publication ,  Journal Article
Baker, JP
Published in: Am J Public Health
February 2000

Childhood immunization constitutes one of the great success stories of American public health in the 20th century. This essay provides a historical examination of this topic through 4 particularly important examples: diphtheria, pertussis, polio, and measles. Each case study illustrates how new vaccines have posed unique challenges related to basic science, clinical trial methodology, medical ethics, and public acceptance. A brief comparison of each story to the experience of Great Britain, however, suggests an underlying unity connecting all 4 examples. Whereas the British led the way in introducing formal clinical trial methodology in the field of immunization development, the Americans excelled in the rapid translation of laboratory knowledge into strategies suitable for mass application. Although this distinction appears to have diminished in recent years, it offers insight into the sources of creativity underlying American vaccine development and the corresponding difficulties sometimes created for utilizing vaccines fruits rationally.

Duke Scholars

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Published In

Am J Public Health

DOI

ISSN

0090-0036

Publication Date

February 2000

Volume

90

Issue

2

Start / End Page

199 / 207

Location

United States

Related Subject Headings

  • United States
  • United Kingdom
  • Risk Assessment
  • Research Subjects
  • Public Health
  • Poliovirus Vaccine, Inactivated
  • Pertussis Vaccine
  • Parental Consent
  • Measles Vaccine
  • Internationality
 

Citation

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Baker, J. P. (2000). Immunization and the American way: 4 childhood vaccines. Am J Public Health, 90(2), 199–207. https://doi.org/10.2105/ajph.90.2.199
Baker, J. P. “Immunization and the American way: 4 childhood vaccines.Am J Public Health 90, no. 2 (February 2000): 199–207. https://doi.org/10.2105/ajph.90.2.199.
Baker JP. Immunization and the American way: 4 childhood vaccines. Am J Public Health. 2000 Feb;90(2):199–207.
Baker, J. P. “Immunization and the American way: 4 childhood vaccines.Am J Public Health, vol. 90, no. 2, Feb. 2000, pp. 199–207. Pubmed, doi:10.2105/ajph.90.2.199.
Baker JP. Immunization and the American way: 4 childhood vaccines. Am J Public Health. 2000 Feb;90(2):199–207.
Journal cover image

Published In

Am J Public Health

DOI

ISSN

0090-0036

Publication Date

February 2000

Volume

90

Issue

2

Start / End Page

199 / 207

Location

United States

Related Subject Headings

  • United States
  • United Kingdom
  • Risk Assessment
  • Research Subjects
  • Public Health
  • Poliovirus Vaccine, Inactivated
  • Pertussis Vaccine
  • Parental Consent
  • Measles Vaccine
  • Internationality