Skip to main content
Journal cover image

Living and deceased donor liver transplantation for unresectable hepatoblastoma at a single center.

Publication ,  Journal Article
Mejia, A; Langnas, AN; Shaw, BW; Torres, C; Sudan, DL
Published in: Clin Transplant
December 2005

Hepatoblastoma (HB) is the most common malignant liver tumor in children. The application of living donor liver transplantation (LDLT) in the management of unresectable HB may add new therapeutic opportunities. We evaluated the outcomes of patients who underwent liver transplantation for treatment of unresectable HB in the period between August 1985 and June 2003. Ten children had a diagnosis of unresectable HB. Mean age at transplantation was 5.8 yr. Eight patients were transplanted with deceased donor grafts. Two patients underwent LDLT. Pre-transplant chemotherapy was used in 90% of cases. Post-transplant survival ranges from 3.7 to 18.6 yr. Three patients died of recurrent disease at 4, 14 and 38 months. The two LDLT recipients were able to get pre-transplant chemotherapy with a rapid decision towards transplantation; both are alive and well at 5.5 and 11 yr post-transplant. Our experience supports the role of LDLT and deceased donor liver transplantation in the management of unresectable HB when waiting times can be detrimental to the patient's survival.

Duke Scholars

Published In

Clin Transplant

DOI

ISSN

0902-0063

Publication Date

December 2005

Volume

19

Issue

6

Start / End Page

721 / 725

Location

Denmark

Related Subject Headings

  • Surgery
  • Retrospective Studies
  • Neoplasm Recurrence, Local
  • Living Donors
  • Liver Transplantation
  • Liver Neoplasms
  • Infant
  • Humans
  • Hepatoblastoma
  • Combined Modality Therapy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Mejia, A., Langnas, A. N., Shaw, B. W., Torres, C., & Sudan, D. L. (2005). Living and deceased donor liver transplantation for unresectable hepatoblastoma at a single center. Clin Transplant, 19(6), 721–725. https://doi.org/10.1111/j.1399-0012.2005.00410.x
Mejia, Alejandro, Alan N. Langnas, Byers W. Shaw, Clarivet Torres, and Debra L. Sudan. “Living and deceased donor liver transplantation for unresectable hepatoblastoma at a single center.Clin Transplant 19, no. 6 (December 2005): 721–25. https://doi.org/10.1111/j.1399-0012.2005.00410.x.
Mejia A, Langnas AN, Shaw BW, Torres C, Sudan DL. Living and deceased donor liver transplantation for unresectable hepatoblastoma at a single center. Clin Transplant. 2005 Dec;19(6):721–5.
Mejia, Alejandro, et al. “Living and deceased donor liver transplantation for unresectable hepatoblastoma at a single center.Clin Transplant, vol. 19, no. 6, Dec. 2005, pp. 721–25. Pubmed, doi:10.1111/j.1399-0012.2005.00410.x.
Mejia A, Langnas AN, Shaw BW, Torres C, Sudan DL. Living and deceased donor liver transplantation for unresectable hepatoblastoma at a single center. Clin Transplant. 2005 Dec;19(6):721–725.
Journal cover image

Published In

Clin Transplant

DOI

ISSN

0902-0063

Publication Date

December 2005

Volume

19

Issue

6

Start / End Page

721 / 725

Location

Denmark

Related Subject Headings

  • Surgery
  • Retrospective Studies
  • Neoplasm Recurrence, Local
  • Living Donors
  • Liver Transplantation
  • Liver Neoplasms
  • Infant
  • Humans
  • Hepatoblastoma
  • Combined Modality Therapy