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Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps.

Publication ,  Journal Article
Schaeffer, SW; Bhutkar, A; McAllister, BF; Matsuda, M; Matzkin, LM; O'Grady, PM; Rohde, C; Valente, VLS; Aguadé, M; Anderson, WW; Edwards, K ...
Published in: Genetics
July 2008

The sequencing of the 12 genomes of members of the genus Drosophila was taken as an opportunity to reevaluate the genetic and physical maps for 11 of the species, in part to aid in the mapping of assembled scaffolds. Here, we present an overview of the importance of cytogenetic maps to Drosophila biology and to the concepts of chromosomal evolution. Physical and genetic markers were used to anchor the genome assembly scaffolds to the polytene chromosomal maps for each species. In addition, a computational approach was used to anchor smaller scaffolds on the basis of the analysis of syntenic blocks. We present the chromosomal map data from each of the 11 sequenced non-Drosophila melanogaster species as a series of sections. Each section reviews the history of the polytene chromosome maps for each species, presents the new polytene chromosome maps, and anchors the genomic scaffolds to the cytological maps using genetic and physical markers. The mapping data agree with Muller's idea that the majority of Drosophila genes are syntenic. Despite the conservation of genes within homologous chromosome arms across species, the karyotypes of these species have changed through the fusion of chromosomal arms followed by subsequent rearrangement events.

Duke Scholars

Published In

Genetics

DOI

EISSN

1943-2631

ISSN

0016-6731

Publication Date

July 2008

Volume

179

Issue

3

Start / End Page

1601 / 1655

Related Subject Headings

  • Synteny
  • Sequence Alignment
  • Physical Chromosome Mapping
  • Karyotyping
  • Genome, Insect
  • Genetic Markers
  • Drosophila
  • Developmental Biology
  • Chromosomes
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Schaeffer, S. W., Bhutkar, A., McAllister, B. F., Matsuda, M., Matzkin, L. M., O’Grady, P. M., … Kaufman, T. C. (2008). Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps. Genetics, 179(3), 1601–1655. https://doi.org/10.1534/genetics.107.086074
Schaeffer, Stephen W., Arjun Bhutkar, Bryant F. McAllister, Muneo Matsuda, Luciano M. Matzkin, Patrick M. O’Grady, Claudia Rohde, et al. “Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps.Genetics 179, no. 3 (July 2008): 1601–55. https://doi.org/10.1534/genetics.107.086074.
Schaeffer SW, Bhutkar A, McAllister BF, Matsuda M, Matzkin LM, O’Grady PM, et al. Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps. Genetics. 2008 Jul;179(3):1601–55.
Schaeffer, Stephen W., et al. “Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps.Genetics, vol. 179, no. 3, July 2008, pp. 1601–55. Epmc, doi:10.1534/genetics.107.086074.
Schaeffer SW, Bhutkar A, McAllister BF, Matsuda M, Matzkin LM, O’Grady PM, Rohde C, Valente VLS, Aguadé M, Anderson WW, Edwards K, Garcia ACL, Goodman J, Hartigan J, Kataoka E, Lapoint RT, Lozovsky ER, Machado CA, Noor MAF, Papaceit M, Reed LK, Richards S, Rieger TT, Russo SM, Sato H, Segarra C, Smith DR, Smith TF, Strelets V, Tobari YN, Tomimura Y, Wasserman M, Watts T, Wilson R, Yoshida K, Markow TA, Gelbart WM, Kaufman TC. Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps. Genetics. 2008 Jul;179(3):1601–1655.

Published In

Genetics

DOI

EISSN

1943-2631

ISSN

0016-6731

Publication Date

July 2008

Volume

179

Issue

3

Start / End Page

1601 / 1655

Related Subject Headings

  • Synteny
  • Sequence Alignment
  • Physical Chromosome Mapping
  • Karyotyping
  • Genome, Insect
  • Genetic Markers
  • Drosophila
  • Developmental Biology
  • Chromosomes
  • Animals