Hyperammonemia associated with perinatal asphyxia.
Publication
, Journal Article
Goldberg, RN; Cabal, LA; Sinatra, FR; Plajstek, CE; Hodgman, JE
Published in: Pediatrics
September 1979
Twelve infants with severe perinatal asphyxia were found to have elevated blood ammonia levels (302 to 960 microgram/100 ml). In the seven survivors, hyperammonemia was associated with CNS irritability, hyperthermia, hypertension, and wide neonatal heart rate oscillations. Follow-up examinations revealed severe neurologic dysfunction in five of seven infants. CNS depression, hyperthermia, hypertension, and a nonreactive, fixed heart rate characterized the infants that died. These findings suggest a clinical entity secondary to perinatal asphyxia whose signs and symptoms may be related to hyperammonemia.
Duke Scholars
Published In
Pediatrics
ISSN
0031-4005
Publication Date
September 1979
Volume
64
Issue
3
Start / End Page
336 / 341
Location
United States
Related Subject Headings
- Pediatrics
- Male
- Infant, Newborn, Diseases
- Infant, Newborn
- Hypertension
- Humans
- Hepatic Encephalopathy
- Heart Rate
- Follow-Up Studies
- Fever
Citation
APA
Chicago
ICMJE
MLA
NLM
Goldberg, R. N., Cabal, L. A., Sinatra, F. R., Plajstek, C. E., & Hodgman, J. E. (1979). Hyperammonemia associated with perinatal asphyxia. Pediatrics, 64(3), 336–341.
Goldberg, R. N., L. A. Cabal, F. R. Sinatra, C. E. Plajstek, and J. E. Hodgman. “Hyperammonemia associated with perinatal asphyxia.” Pediatrics 64, no. 3 (September 1979): 336–41.
Goldberg RN, Cabal LA, Sinatra FR, Plajstek CE, Hodgman JE. Hyperammonemia associated with perinatal asphyxia. Pediatrics. 1979 Sep;64(3):336–41.
Goldberg, R. N., et al. “Hyperammonemia associated with perinatal asphyxia.” Pediatrics, vol. 64, no. 3, Sept. 1979, pp. 336–41.
Goldberg RN, Cabal LA, Sinatra FR, Plajstek CE, Hodgman JE. Hyperammonemia associated with perinatal asphyxia. Pediatrics. 1979 Sep;64(3):336–341.
Published In
Pediatrics
ISSN
0031-4005
Publication Date
September 1979
Volume
64
Issue
3
Start / End Page
336 / 341
Location
United States
Related Subject Headings
- Pediatrics
- Male
- Infant, Newborn, Diseases
- Infant, Newborn
- Hypertension
- Humans
- Hepatic Encephalopathy
- Heart Rate
- Follow-Up Studies
- Fever