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A comparison of grating visual acuity, strabismus, and reoperation outcomes among children with aphakia and pseudophakia after unilateral cataract surgery during the first six months of life.

Publication ,  Journal Article
Lambert, SR; Lynn, M; Drews-Botsch, C; Loupe, D; Plager, DA; Medow, NB; Wilson, ME; Buckley, EG; Drack, AV; Fawcett, SL
Published in: J AAPOS
April 2001

PURPOSE: The method of correcting aphakia after unilateral cataract extraction during infancy is controversial. Some authorities advocate correction with an intraocular lens (IOL) whereas others advocate correction with a contact lens (CL). We compared grating visual acuity, alignment, and reoperative outcomes in age-matched children treated with these 2 modalities at 5 clinical centers. METHODS: Twenty-five infants born in 1997 or 1998 with a dense unilateral congenital cataract who had cataract surgery coupled with (IOL group, n = 12) or without (CL group, n = 13) primary IOL implantation were enrolled in this study. All patients were prescribed half-time occlusion therapy. In July 1999, their grating visual acuities, ocular alignments, and reoperation rates were assessed. RESULTS: The mean grating visual acuity (LogMAR) for the affected eye was 0.70 +/- 0.32 for the IOL group and 0.87 +/- 0.31 for the CL group (P =.19). The mean interocular difference in grating visual acuity was 0.26 +/- 0.30 for the IOL group and 0.50 +/- 0.28 for the CL group (P =.048). The incidence of strabismus (>10 PD) was 75% in the IOL group compared with 92% in the CL group (P =.24). The incidence of reoperations was 83% in the IOL group compared with 23% in the CL group (P =.003). CONCLUSIONS: Our preliminary data suggest that correcting aphakia after unilateral congenital cataract surgery with primary IOL implantation results in an improved visual outcome but a higher rate of complications requiring reoperation. A randomized clinical trial, the Infant Aphakia Treatment Study, is planned to further study the optimal treatment for aphakia following unilateral cataract extraction during infancy.

Duke Scholars

Published In

J AAPOS

DOI

ISSN

1091-8531

Publication Date

April 2001

Volume

5

Issue

2

Start / End Page

70 / 75

Location

United States

Related Subject Headings

  • Visual Acuity
  • Treatment Outcome
  • Strabismus
  • Sensory Deprivation
  • Reoperation
  • Pseudophakia
  • Ophthalmology & Optometry
  • Lens Implantation, Intraocular
  • Infant
  • Incidence
 

Citation

APA
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ICMJE
MLA
NLM
Lambert, S. R., Lynn, M., Drews-Botsch, C., Loupe, D., Plager, D. A., Medow, N. B., … Fawcett, S. L. (2001). A comparison of grating visual acuity, strabismus, and reoperation outcomes among children with aphakia and pseudophakia after unilateral cataract surgery during the first six months of life. J AAPOS, 5(2), 70–75. https://doi.org/10.1067/mpa.2001.111015
Lambert, S. R., M. Lynn, C. Drews-Botsch, D. Loupe, D. A. Plager, N. B. Medow, M. E. Wilson, E. G. Buckley, A. V. Drack, and S. L. Fawcett. “A comparison of grating visual acuity, strabismus, and reoperation outcomes among children with aphakia and pseudophakia after unilateral cataract surgery during the first six months of life.J AAPOS 5, no. 2 (April 2001): 70–75. https://doi.org/10.1067/mpa.2001.111015.
Lambert SR, Lynn M, Drews-Botsch C, Loupe D, Plager DA, Medow NB, Wilson ME, Buckley EG, Drack AV, Fawcett SL. A comparison of grating visual acuity, strabismus, and reoperation outcomes among children with aphakia and pseudophakia after unilateral cataract surgery during the first six months of life. J AAPOS. 2001 Apr;5(2):70–75.
Journal cover image

Published In

J AAPOS

DOI

ISSN

1091-8531

Publication Date

April 2001

Volume

5

Issue

2

Start / End Page

70 / 75

Location

United States

Related Subject Headings

  • Visual Acuity
  • Treatment Outcome
  • Strabismus
  • Sensory Deprivation
  • Reoperation
  • Pseudophakia
  • Ophthalmology & Optometry
  • Lens Implantation, Intraocular
  • Infant
  • Incidence