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Gain in signal-to-noise for first-pass contrast-enhanced abdominal MR angiography at 3 Tesla over standard 1.5 Tesla: prediction with a computer model.

Publication ,  Journal Article
Merkle, EM; Dale, BM; Barboriak, DP
Published in: Acad Radiol
July 2007

RATIONALE AND OBJECTIVES: To estimate the gain in signal-to-noise ratio (SNR) in first-pass contrast-enhanced (CE) abdominal magnetic resonance angiography (MRA) at 3.0 T compared with 1.5 T. MATERIALS AND METHODS: Three protocols were simulated using six contrast agents: gadopentetate dimeglumine (Magnevist, Berlex, Wayne, NJ), gadoteridol (Prohance, Bracco, Princeton, NJ), gadobenate dimeglumine (Multihance, Bracco, Princeton, NJ), gadodiamide (Omniscan, Amersham Health, Princeton, NJ), gadoversetamide (Optimark, Mallinckrodt, St. Louis, MO), and gadofosveset trisodium (MS-325, EPIX Medical, Cambridge, MA). Contrast concentrations were calculated for five abdominal vessels. Based on these data, the gain in SNR during CE abdominal MRA at 3.0 T over 1.5 T was estimated. RESULTS: In these simulations, peak concentrations in all five target vessels were about 5 mM, 10 mM, and 0.7 mM for protocol 1, protocol 2, and protocol 3, respectively. A gain in SNR at 3 T over 1.5 T during CE abdominal MRA of at least 94% in all five target vessels could be achieved by applying protocol 1 or protocol 2, whereas protocol 3 provided a gain in SNR of 70%. CONCLUSIONS: Although five of the contrast agents studied fulfill the expectation of providing approximately twice the SNR at 3.0 T versus 1.5 T during CE abdominal MRA, MS-325 offers a gain in SNR of 70% only.

Duke Scholars

Published In

Acad Radiol

DOI

ISSN

1076-6332

Publication Date

July 2007

Volume

14

Issue

7

Start / End Page

795 / 803

Location

United States

Related Subject Headings

  • Signal Processing, Computer-Assisted
  • Predictive Value of Tests
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Models, Biological
  • Middle Aged
  • Meglumine
  • Male
  • Magnetics
  • Magnetic Resonance Angiography
 

Citation

APA
Chicago
ICMJE
MLA
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Merkle, E. M., Dale, B. M., & Barboriak, D. P. (2007). Gain in signal-to-noise for first-pass contrast-enhanced abdominal MR angiography at 3 Tesla over standard 1.5 Tesla: prediction with a computer model. Acad Radiol, 14(7), 795–803. https://doi.org/10.1016/j.acra.2007.03.007
Merkle, Elmar Max, Brian Marshall Dale, and Daniel Paul Barboriak. “Gain in signal-to-noise for first-pass contrast-enhanced abdominal MR angiography at 3 Tesla over standard 1.5 Tesla: prediction with a computer model.Acad Radiol 14, no. 7 (July 2007): 795–803. https://doi.org/10.1016/j.acra.2007.03.007.
Merkle, Elmar Max, et al. “Gain in signal-to-noise for first-pass contrast-enhanced abdominal MR angiography at 3 Tesla over standard 1.5 Tesla: prediction with a computer model.Acad Radiol, vol. 14, no. 7, July 2007, pp. 795–803. Pubmed, doi:10.1016/j.acra.2007.03.007.
Journal cover image

Published In

Acad Radiol

DOI

ISSN

1076-6332

Publication Date

July 2007

Volume

14

Issue

7

Start / End Page

795 / 803

Location

United States

Related Subject Headings

  • Signal Processing, Computer-Assisted
  • Predictive Value of Tests
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Models, Biological
  • Middle Aged
  • Meglumine
  • Male
  • Magnetics
  • Magnetic Resonance Angiography