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Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO).

Publication ,  Journal Article
Smith, BD; Arthur, DW; Buchholz, TA; Haffty, BG; Hahn, CA; Hardenbergh, PH; Julian, TB; Marks, LB; Todor, DA; Vicini, FA; Whelan, TJ; White, J ...
Published in: Int J Radiat Oncol Biol Phys
July 15, 2009

PURPOSE: To present guidance for patients and physicians regarding the use of accelerated partial-breast irradiation (APBI), based on current published evidence complemented by expert opinion. METHODS AND MATERIALS: A systematic search of the National Library of Medicine's PubMed database yielded 645 candidate original research articles potentially applicable to APBI. Of these, 4 randomized trials and 38 prospective single-arm studies were identified. A Task Force composed of all authors synthesized the published evidence and, through a series of meetings, reached consensus regarding the recommendations contained herein. RESULTS: The Task Force proposed three patient groups: (1) a "suitable" group, for whom APBI outside of a clinical trial is acceptable, (2) a "cautionary" group, for whom caution and concern should be applied when considering APBI outside of a clinical trial, and (3) an "unsuitable" group, for whom APBI outside of a clinical trial is not generally considered warranted. Patients who choose treatment with APBI should be informed that whole-breast irradiation (WBI) is an established treatment with a much longer track record that has documented long-term effectiveness and safety. CONCLUSION: Accelerated partial-breast irradiation is a new technology that may ultimately demonstrate long-term effectiveness and safety comparable to that of WBI for selected patients with early breast cancer. This consensus statement is intended to provide guidance regarding the use of APBI outside of a clinical trial and to serve as a framework to promote additional clinical investigations into the optimal role of APBI in the treatment of breast cancer.

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Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

July 15, 2009

Volume

74

Issue

4

Start / End Page

987 / 1001

Location

United States

Related Subject Headings

  • United States
  • Societies, Medical
  • Radiotherapy Dosage
  • Radiation Oncology
  • Patient Selection
  • Oncology & Carcinogenesis
  • Mastectomy, Segmental
  • Informed Consent
  • Humans
  • Female
 

Citation

APA
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ICMJE
MLA
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Smith, B. D., Arthur, D. W., Buchholz, T. A., Haffty, B. G., Hahn, C. A., Hardenbergh, P. H., … Harris, J. R. (2009). Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO). Int J Radiat Oncol Biol Phys, 74(4), 987–1001. https://doi.org/10.1016/j.ijrobp.2009.02.031
Smith, Benjamin D., Douglas W. Arthur, Thomas A. Buchholz, Bruce G. Haffty, Carol A. Hahn, Patricia H. Hardenbergh, Thomas B. Julian, et al. “Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO).Int J Radiat Oncol Biol Phys 74, no. 4 (July 15, 2009): 987–1001. https://doi.org/10.1016/j.ijrobp.2009.02.031.
Smith BD, Arthur DW, Buchholz TA, Haffty BG, Hahn CA, Hardenbergh PH, et al. Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO). Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):987–1001.
Smith, Benjamin D., et al. “Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO).Int J Radiat Oncol Biol Phys, vol. 74, no. 4, July 2009, pp. 987–1001. Pubmed, doi:10.1016/j.ijrobp.2009.02.031.
Smith BD, Arthur DW, Buchholz TA, Haffty BG, Hahn CA, Hardenbergh PH, Julian TB, Marks LB, Todor DA, Vicini FA, Whelan TJ, White J, Wo JY, Harris JR. Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO). Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):987–1001.
Journal cover image

Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

July 15, 2009

Volume

74

Issue

4

Start / End Page

987 / 1001

Location

United States

Related Subject Headings

  • United States
  • Societies, Medical
  • Radiotherapy Dosage
  • Radiation Oncology
  • Patient Selection
  • Oncology & Carcinogenesis
  • Mastectomy, Segmental
  • Informed Consent
  • Humans
  • Female