Multiplex detection of breast cancer biomarkers using plasmonic molecular sentinel nanoprobes
Publication
, Journal Article
Wang, HN; Vo dinh, T
Published in: Nanotechnology
February 2009
We have demonstrated for the first time the feasibility of multiplex detection using the surface-enhanced Raman scattering-based molecular sentinel ( MS) technology in a homogeneous solution. Two MS nanoprobes tagged with different Raman labels were used to detect the presence of the erbB-2 and ki-67 breast cancer biomarkers. The multiplexing capability of the MS technique was demonstrated by mixing the two MS nanoprobes and tested in the presence of single or multiple DNA targets.
Duke Scholars
Published In
Nanotechnology
ISSN
0957-4484
Publication Date
February 2009
Volume
20
Issue
6
Related Subject Headings
- Spectrum Analysis, Raman
- Receptor, erbB-2
- Receptor, ErbB-2
- Nucleic Acid Hybridization
- Nanotechnology
- Nanoscience & Nanotechnology
- Ki-67 Antigen
- Humans
- Clinical Laboratory Techniques
- Breast Neoplasms
Citation
APA
Chicago
ICMJE
MLA
NLM
Wang, H. N., & Vo dinh, T. (2009). Multiplex detection of breast cancer biomarkers using plasmonic molecular sentinel nanoprobes. Nanotechnology, 20(6).
Wang, H. N., and T. Vo dinh. “Multiplex detection of breast cancer biomarkers using plasmonic molecular sentinel nanoprobes.” Nanotechnology 20, no. 6 (February 2009).
Wang HN, Vo dinh T. Multiplex detection of breast cancer biomarkers using plasmonic molecular sentinel nanoprobes. Nanotechnology. 2009 Feb;20(6).
Wang, H. N., and T. Vo dinh. “Multiplex detection of breast cancer biomarkers using plasmonic molecular sentinel nanoprobes.” Nanotechnology, vol. 20, no. 6, Feb. 2009.
Wang HN, Vo dinh T. Multiplex detection of breast cancer biomarkers using plasmonic molecular sentinel nanoprobes. Nanotechnology. 2009 Feb;20(6).
Published In
Nanotechnology
ISSN
0957-4484
Publication Date
February 2009
Volume
20
Issue
6
Related Subject Headings
- Spectrum Analysis, Raman
- Receptor, erbB-2
- Receptor, ErbB-2
- Nucleic Acid Hybridization
- Nanotechnology
- Nanoscience & Nanotechnology
- Ki-67 Antigen
- Humans
- Clinical Laboratory Techniques
- Breast Neoplasms