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Long-term follow-up of men with male pattern baldness treated with topical minoxidil.

Publication ,  Journal Article
Olsen, EA; DeLong, ER; Weiner, MS
Published in: J Am Acad Dermatol
March 1987

Forty-one men with male pattern baldness completed 132 study weeks (2 years 9 months) with topical minoxidil and had follow-up 1-inch target-area vertex scalp hair counts. Initially these men were treated with either twice-daily 2% topical minoxidil for 12 months or 3% topical minoxidil for 8 to 12 months (one third of the subjects received placebo for the first 4 months). After 12 months all subjects continued to apply 3% topical minoxidil twice daily for 1 more year, after which they were randomized to once- versus twice-daily topical minoxidil for an additional 9 months. Those subjects who changed to once-daily application of topical minoxidil at 2 years had a mean change from baseline nonvellus hair count at 1 year of 291.2 (range of hairs four to 553) and at 2 years 9 months of 235 (two to 592 hairs). Those subjects who continued with twice-daily application of topical minoxidil throughout the study had a mean change from baseline nonvellus hair count at 1 year of 323 (15 to 589 hairs) and 335 (13 to 808 hairs) at 2 years 9 months with maintenance topical minoxidil. There were subjects on both maintenance schedules of topical minoxidil who lost some of the nonvellus hair they had initially gained with topical minoxidil; however, there was a greater mean loss in those patients following the once-daily versus twice-daily topical minoxidil regimen (p = 0.05). No subject lost nonvellus target hair as compared with baseline.(ABSTRACT TRUNCATED AT 250 WORDS)

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Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

March 1987

Volume

16

Issue

3 Pt 2

Start / End Page

688 / 695

Location

United States

Related Subject Headings

  • Time Factors
  • Random Allocation
  • Minoxidil
  • Middle Aged
  • Male
  • Humans
  • Follow-Up Studies
  • Drug Administration Schedule
  • Dermatology & Venereal Diseases
  • Clinical Trials as Topic
 

Citation

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Olsen, E. A., DeLong, E. R., & Weiner, M. S. (1987). Long-term follow-up of men with male pattern baldness treated with topical minoxidil. J Am Acad Dermatol, 16(3 Pt 2), 688–695. https://doi.org/10.1016/s0190-9622(87)70089-9
Olsen, E. A., E. R. DeLong, and M. S. Weiner. “Long-term follow-up of men with male pattern baldness treated with topical minoxidil.J Am Acad Dermatol 16, no. 3 Pt 2 (March 1987): 688–95. https://doi.org/10.1016/s0190-9622(87)70089-9.
Olsen EA, DeLong ER, Weiner MS. Long-term follow-up of men with male pattern baldness treated with topical minoxidil. J Am Acad Dermatol. 1987 Mar;16(3 Pt 2):688–95.
Olsen, E. A., et al. “Long-term follow-up of men with male pattern baldness treated with topical minoxidil.J Am Acad Dermatol, vol. 16, no. 3 Pt 2, Mar. 1987, pp. 688–95. Pubmed, doi:10.1016/s0190-9622(87)70089-9.
Olsen EA, DeLong ER, Weiner MS. Long-term follow-up of men with male pattern baldness treated with topical minoxidil. J Am Acad Dermatol. 1987 Mar;16(3 Pt 2):688–695.
Journal cover image

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

March 1987

Volume

16

Issue

3 Pt 2

Start / End Page

688 / 695

Location

United States

Related Subject Headings

  • Time Factors
  • Random Allocation
  • Minoxidil
  • Middle Aged
  • Male
  • Humans
  • Follow-Up Studies
  • Drug Administration Schedule
  • Dermatology & Venereal Diseases
  • Clinical Trials as Topic