Skip to main content

The relationship between glycemic control and health-related quality of life in patients with non-insulin-dependent diabetes mellitus.

Publication ,  Journal Article
Weinberger, M; Kirkman, MS; Samsa, GP; Cowper, PA; Shortliffe, EA; Simel, DL; Feussner, JR
Published in: Med Care
December 1994

The relationship between glycemic control and health-related quality of life was examined in patients with non-insulin-dependent diabetes mellitus (NIDDM). Within the context of a randomized controlled trial, 275 patients with NIDDM receiving primary care from a Veteran's Administration general medical clinic were enrolled and monitored for 1 year. Glycemic control (glycosylated hemoglobin levels) and health-related quality of life (Medical Outcomes Study Short-Form 36-item Health Survey [SF-36]) were assessed at baseline and at 1 year. Multivariate regression modeling using baseline and change scores during a 1-year period did not find a linear or curvilinear relationship between glycosylated hemoglobin and SF-36 scores (P = .15); this was true even after controlling for five covariates identified a priori (insulin use, number of diabetic complications, duration of diabetes, education, number of hyper-, or hypoglycemic episodes during the preceding month). Health services researchers and clinicians alike need to be aware that these two important outcomes may not be directly related. This lack of association could contribute to the high noncompliance rates observed among patients prescribed complex diabetic regimens. Unless patients perceive a benefit from following such regimens, good glycemic control may continue to be an elusive therapeutic goal, especially in patients with long-standing disease.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Med Care

DOI

ISSN

0025-7079

Publication Date

December 1994

Volume

32

Issue

12

Start / End Page

1173 / 1181

Location

United States

Related Subject Headings

  • Regression Analysis
  • Quality of Life
  • Patient Compliance
  • North Carolina
  • Middle Aged
  • Male
  • Humans
  • Hospitals, Veterans
  • Health Status
  • Health Policy & Services
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Weinberger, M., Kirkman, M. S., Samsa, G. P., Cowper, P. A., Shortliffe, E. A., Simel, D. L., & Feussner, J. R. (1994). The relationship between glycemic control and health-related quality of life in patients with non-insulin-dependent diabetes mellitus. Med Care, 32(12), 1173–1181. https://doi.org/10.1097/00005650-199412000-00002
Weinberger, M., M. S. Kirkman, G. P. Samsa, P. A. Cowper, E. A. Shortliffe, D. L. Simel, and J. R. Feussner. “The relationship between glycemic control and health-related quality of life in patients with non-insulin-dependent diabetes mellitus.Med Care 32, no. 12 (December 1994): 1173–81. https://doi.org/10.1097/00005650-199412000-00002.
Weinberger M, Kirkman MS, Samsa GP, Cowper PA, Shortliffe EA, Simel DL, et al. The relationship between glycemic control and health-related quality of life in patients with non-insulin-dependent diabetes mellitus. Med Care. 1994 Dec;32(12):1173–81.
Weinberger, M., et al. “The relationship between glycemic control and health-related quality of life in patients with non-insulin-dependent diabetes mellitus.Med Care, vol. 32, no. 12, Dec. 1994, pp. 1173–81. Pubmed, doi:10.1097/00005650-199412000-00002.
Weinberger M, Kirkman MS, Samsa GP, Cowper PA, Shortliffe EA, Simel DL, Feussner JR. The relationship between glycemic control and health-related quality of life in patients with non-insulin-dependent diabetes mellitus. Med Care. 1994 Dec;32(12):1173–1181.

Published In

Med Care

DOI

ISSN

0025-7079

Publication Date

December 1994

Volume

32

Issue

12

Start / End Page

1173 / 1181

Location

United States

Related Subject Headings

  • Regression Analysis
  • Quality of Life
  • Patient Compliance
  • North Carolina
  • Middle Aged
  • Male
  • Humans
  • Hospitals, Veterans
  • Health Status
  • Health Policy & Services