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Racial differences in enrolment in a cancer genetics registry.

Publication ,  Journal Article
Moorman, PG; Skinner, CS; Evans, JP; Newman, B; Sorenson, JR; Calingaert, B; Susswein, L; Crankshaw, TS; Hoyo, C; Schildkraut, JM
Published in: Cancer Epidemiol Biomarkers Prev
August 2004

BACKGROUND: Lower enrolment of minorities into research studies has been reported frequently. Most studies have little information about nonparticipants, making it difficult to identify characteristics associated with enrolment and how they might vary by race. METHODS: Women who had previously participated in a population-based, case-control study of breast cancer in North Carolina were invited to enroll in a cancer genetics registry. Detailed questionnaire data on sociodemographic characteristics and cancer risk factors were available for all women. We compared characteristics of women who agreed to be in the registry with those who were deceased, were unlocatable, or declined enrolment. Unconditional logistic regression analyses were done to identify predictors of enrolment. RESULTS: Enrolment rates were markedly lower among African Americans than Whites (15% and 36%, respectively) due to both lower contact rates (41% versus 63%) and lower enrolment rates among those contacted (37% versus 58%). Logistic regression models suggested that racial differences in enrolment were not due to socioeconomic characteristics or other cancer risk factors; race was the only significant predictor of enrolment in multivariable models (odds ratio 0.41, 95% confidence interval 0.23-0.72). CONCLUSIONS: Although all women had previously taken part in a research study, African American women were less likely to enroll in the cancer genetics registry than White women. A possible explanation of these findings is that studies of genetics may present particular concerns for African Americans. Further research is needed to identify attitudes and issues that present barriers to participation among minorities.

Duke Scholars

Published In

Cancer Epidemiol Biomarkers Prev

ISSN

1055-9965

Publication Date

August 2004

Volume

13

Issue

8

Start / End Page

1349 / 1354

Location

United States

Related Subject Headings

  • White People
  • Surveys and Questionnaires
  • Socioeconomic Factors
  • Risk Assessment
  • Research
  • Registries
  • Probability
  • Prevalence
  • Patient Selection
  • Minority Groups
 

Citation

APA
Chicago
ICMJE
MLA
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Moorman, P. G., Skinner, C. S., Evans, J. P., Newman, B., Sorenson, J. R., Calingaert, B., … Schildkraut, J. M. (2004). Racial differences in enrolment in a cancer genetics registry. Cancer Epidemiol Biomarkers Prev, 13(8), 1349–1354.
Moorman, Patricia G., Celette Sugg Skinner, James P. Evans, Beth Newman, James R. Sorenson, Brian Calingaert, Lisa Susswein, T Sydnee Crankshaw, Cathrine Hoyo, and Joellen M. Schildkraut. “Racial differences in enrolment in a cancer genetics registry.Cancer Epidemiol Biomarkers Prev 13, no. 8 (August 2004): 1349–54.
Moorman PG, Skinner CS, Evans JP, Newman B, Sorenson JR, Calingaert B, et al. Racial differences in enrolment in a cancer genetics registry. Cancer Epidemiol Biomarkers Prev. 2004 Aug;13(8):1349–54.
Moorman, Patricia G., et al. “Racial differences in enrolment in a cancer genetics registry.Cancer Epidemiol Biomarkers Prev, vol. 13, no. 8, Aug. 2004, pp. 1349–54.
Moorman PG, Skinner CS, Evans JP, Newman B, Sorenson JR, Calingaert B, Susswein L, Crankshaw TS, Hoyo C, Schildkraut JM. Racial differences in enrolment in a cancer genetics registry. Cancer Epidemiol Biomarkers Prev. 2004 Aug;13(8):1349–1354.

Published In

Cancer Epidemiol Biomarkers Prev

ISSN

1055-9965

Publication Date

August 2004

Volume

13

Issue

8

Start / End Page

1349 / 1354

Location

United States

Related Subject Headings

  • White People
  • Surveys and Questionnaires
  • Socioeconomic Factors
  • Risk Assessment
  • Research
  • Registries
  • Probability
  • Prevalence
  • Patient Selection
  • Minority Groups