Scholars@Duke publication: Decisional conflict among patients who accept or decline participation in phase I oncology studies.

Decisional conflict among patients who accept or decline participation in phase I oncology studies.

Publication , Journal Article

Flynn, KE; Weinfurt, KP; Seils, DM; Lin, L; Burnett, CB; Schulman, KA; Meropol, NJ

Published in: J Empir Res Hum Res Ethics

September 2008

WE COMPARED DECISIONAL CONFLICT among adults with advanced cancer who had accepted or declined participation in phase I cancer clinical trials. Respondents completed a 121-item questionnaire that included the Decisional Conflict Scale (DCS), which was designed to measure uncertainty in making health decisions. We used standardized effect sizes to compare the DCS scores of accepters (n = 250) and decliners (n = 65). Accepters had lower decisional conflict than decliners overall (d = 0.42; 95% confidence interval, 0.17--0.68) and on all subscales. Whether greater decisional conflict among decliners represents suboptimal decision-making and is reason for bioethical concern depends on how the results are interpreted. We offer three scenarios to explain the differences and describe opportunities for future empirical work.

Duke Scholars

Author Kathryn Eve Flynn Population Health Sciences

Author Kevin Phillip Weinfurt Population Health Sciences

Published In

J Empir Res Hum Res Ethics

DOI

10.1525/jer.2008.3.3.69

ISSN

1556-2646

Publication Date

September 2008

Volume

Issue

Start / End Page

69 / 77

Location

United States

Related Subject Headings

5001 Applied ethics
2201 Applied Ethics
1799 Other Psychology and Cognitive Sciences
1701 Psychology

Citation

APA

Chicago

ICMJE

MLA

NLM

Flynn, K. E., Weinfurt, K. P., Seils, D. M., Lin, L., Burnett, C. B., Schulman, K. A., & Meropol, N. J. (2008). Decisional conflict among patients who accept or decline participation in phase I oncology studies. J Empir Res Hum Res Ethics, 3(3), 69–77. https://doi.org/10.1525/jer.2008.3.3.69

Flynn, Kathryn E., Kevin P. Weinfurt, Damon M. Seils, Li Lin, Caroline B. Burnett, Kevin A. Schulman, and Neal J. Meropol. “Decisional conflict among patients who accept or decline participation in phase I oncology studies.” J Empir Res Hum Res Ethics 3, no. 3 (September 2008): 69–77. https://doi.org/10.1525/jer.2008.3.3.69.

Flynn KE, Weinfurt KP, Seils DM, Lin L, Burnett CB, Schulman KA, et al. Decisional conflict among patients who accept or decline participation in phase I oncology studies. J Empir Res Hum Res Ethics. 2008 Sep;3(3):69–77.

Flynn, Kathryn E., et al. “Decisional conflict among patients who accept or decline participation in phase I oncology studies.” J Empir Res Hum Res Ethics, vol. 3, no. 3, Sept. 2008, pp. 69–77. Pubmed, doi:10.1525/jer.2008.3.3.69.

Flynn KE, Weinfurt KP, Seils DM, Lin L, Burnett CB, Schulman KA, Meropol NJ. Decisional conflict among patients who accept or decline participation in phase I oncology studies. J Empir Res Hum Res Ethics. 2008 Sep;3(3):69–77.

Published In

J Empir Res Hum Res Ethics

DOI

10.1525/jer.2008.3.3.69

ISSN

1556-2646

Publication Date

September 2008

Volume

Issue

Start / End Page

69 / 77

Location

United States

Related Subject Headings

5001 Applied ethics
2201 Applied Ethics
1799 Other Psychology and Cognitive Sciences
1701 Psychology