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Childhood neuropsychological deficits associated with adult obsessive-compulsive disorder.

Publication ,  Journal Article
Grisham, JR; Anderson, TM; Poulton, R; Moffitt, TE; Andrews, G
Published in: The British journal of psychiatry : the journal of mental science
August 2009

Existing neuropsychological studies of obsessive-compulsive disorder (OCD) are cross-sectional and do not provide evidence of whether deficits are trait-related (antecedent and independent of symptomatology) or state-related (a consequence, dependent on symptomatology).To investigate whether there are premorbid neuropsychological deficits associated with adult OCD.Longitudinal data were collected from participants of the Dunedin Multidisciplinary Health and Developmental study. Neuropsychological data collected at age 13 were linked with age 32 diagnosis of OCD.The group who had OCD at age 32 differed significantly from the control group with no OCD on their performance at age 13 on neuropsychological tests of visuospatial, visuoconstructive and visuomotor skills, controlling for gender and socioeconomic status, but did not differ on tests of general IQ or verbal ability. Performance of the group with OCD on tests of executive functioning was mixed.Individuals with OCD have premorbid impairment in visuospatial abilities and some forms of executive functioning, consistent with biological models of OCD.

Duke Scholars

Published In

The British journal of psychiatry : the journal of mental science

DOI

EISSN

1472-1465

ISSN

0007-1250

Publication Date

August 2009

Volume

195

Issue

2

Start / End Page

138 / 141

Related Subject Headings

  • Visual Perception
  • Spatial Behavior
  • Psychomotor Performance
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Obsessive-Compulsive Disorder
  • Neuropsychological Tests
  • Male
  • Longitudinal Studies
  • Logistic Models
 

Citation

APA
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ICMJE
MLA
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Grisham, J. R., Anderson, T. M., Poulton, R., Moffitt, T. E., & Andrews, G. (2009). Childhood neuropsychological deficits associated with adult obsessive-compulsive disorder. The British Journal of Psychiatry : The Journal of Mental Science, 195(2), 138–141. https://doi.org/10.1192/bjp.bp.108.056812
Grisham, Jessica R., Tracy M. Anderson, Richie Poulton, Terrie E. Moffitt, and Gavin Andrews. “Childhood neuropsychological deficits associated with adult obsessive-compulsive disorder.The British Journal of Psychiatry : The Journal of Mental Science 195, no. 2 (August 2009): 138–41. https://doi.org/10.1192/bjp.bp.108.056812.
Grisham JR, Anderson TM, Poulton R, Moffitt TE, Andrews G. Childhood neuropsychological deficits associated with adult obsessive-compulsive disorder. The British journal of psychiatry : the journal of mental science. 2009 Aug;195(2):138–41.
Grisham, Jessica R., et al. “Childhood neuropsychological deficits associated with adult obsessive-compulsive disorder.The British Journal of Psychiatry : The Journal of Mental Science, vol. 195, no. 2, Aug. 2009, pp. 138–41. Epmc, doi:10.1192/bjp.bp.108.056812.
Grisham JR, Anderson TM, Poulton R, Moffitt TE, Andrews G. Childhood neuropsychological deficits associated with adult obsessive-compulsive disorder. The British journal of psychiatry : the journal of mental science. 2009 Aug;195(2):138–141.
Journal cover image

Published In

The British journal of psychiatry : the journal of mental science

DOI

EISSN

1472-1465

ISSN

0007-1250

Publication Date

August 2009

Volume

195

Issue

2

Start / End Page

138 / 141

Related Subject Headings

  • Visual Perception
  • Spatial Behavior
  • Psychomotor Performance
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Obsessive-Compulsive Disorder
  • Neuropsychological Tests
  • Male
  • Longitudinal Studies
  • Logistic Models