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The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum-type atrial septal defect in adults.

Publication ,  Journal Article
Siddiqui, AM; Samad, Z; Hakacova, N; Kinsella, J; Ward, C; White, M; Crowley, ALC; Wagner, GS; Harrison, JK
Published in: J Electrocardiol
2010

BACKGROUND: This study was performed to test the hypothesis that there exists a correlation between the Butler-Leggett (BL) criterion for right ventricular hypertrophy on the electrocardiogram and the Qp/Qs shunt ratio in adults with ostium secundum atrial septal defects (ASDs). METHODS: Demographic, cardiac catheterization, ASD closure, and electrocardiographic data were acquired on 70 patients with secundum ASDs closed percutaneously. Simple linear regression and logistic regression models were created to test the hypothesis. RESULTS: The mean Qp/Qs ratio and BL criterion value were 1.61 +/- 0.46 and 0.11 +/- 0.41, respectively. The BL criterion values correlated with shunt ratios (r(2) = 0.11 and P = .004). A BL criterion value greater than 0 mV predicted a significant shunt ratio (Qp/Qs > or = 1.5) (odds ratio, 4.8; 95% confidence interval, 1.3, 18.1; P = or <.0001) with a sensitivity of 0.68 and specificity of 0.65. CONCLUSION: Our results indicate that there is limited utility of the BL criterion at detecting right ventricular volume overload, although a BL criterion value greater than 0 mV being used to identify patients with significant intracardiac shunts yielded a sensitivity of 0.68 and specificity of 0.65.

Duke Scholars

Published In

J Electrocardiol

DOI

EISSN

1532-8430

Publication Date

2010

Volume

43

Issue

2

Start / End Page

161 / 166

Location

United States

Related Subject Headings

  • Young Adult
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Middle Aged
  • Male
  • Hypertrophy, Right Ventricular
  • Humans
  • Heart Septal Defects, Atrial
  • Female
  • Electrocardiography
 

Citation

APA
Chicago
ICMJE
MLA
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Siddiqui, A. M., Samad, Z., Hakacova, N., Kinsella, J., Ward, C., White, M., … Harrison, J. K. (2010). The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum-type atrial septal defect in adults. J Electrocardiol, 43(2), 161–166. https://doi.org/10.1016/j.jelectrocard.2009.10.001
Siddiqui, Adeel M., Zainab Samad, Nina Hakacova, James Kinsella, Cary Ward, Michael White, Anna Lisa C. Crowley, Galen S. Wagner, and J Kevin Harrison. “The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum-type atrial septal defect in adults.J Electrocardiol 43, no. 2 (2010): 161–66. https://doi.org/10.1016/j.jelectrocard.2009.10.001.
Siddiqui, Adeel M., et al. “The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum-type atrial septal defect in adults.J Electrocardiol, vol. 43, no. 2, 2010, pp. 161–66. Pubmed, doi:10.1016/j.jelectrocard.2009.10.001.
Siddiqui AM, Samad Z, Hakacova N, Kinsella J, Ward C, White M, Crowley ALC, Wagner GS, Harrison JK. The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum-type atrial septal defect in adults. J Electrocardiol. 2010;43(2):161–166.
Journal cover image

Published In

J Electrocardiol

DOI

EISSN

1532-8430

Publication Date

2010

Volume

43

Issue

2

Start / End Page

161 / 166

Location

United States

Related Subject Headings

  • Young Adult
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Middle Aged
  • Male
  • Hypertrophy, Right Ventricular
  • Humans
  • Heart Septal Defects, Atrial
  • Female
  • Electrocardiography