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Renal allograft rejection: evaluation by Doppler US and MR imaging.

Publication ,  Journal Article
Steinberg, HV; Nelson, RC; Murphy, FB; Chezmar, JL; Baumgartner, BR; Delaney, VB; Whelchel, JD; Bernardino, ME
Published in: Radiology
February 1987

A prospective study compared the efficacy of Doppler ultrasonography (US) and magnetic resonance (MR) imaging in evaluating 38 renal allografts, with specific attention to transplant rejection. Forty-three Doppler US and 42 MR examinations were performed and interpreted. Histologic correlation was obtained from 22 biopsy or nephrectomy specimens. Clinical correlation or a response to instituted therapy was used as confirmation in the remaining allografts. Accuracy in identifying cyclosporine toxicity or acute tubular necrosis could not be evaluated because there were few such cases, with concomitant rejection in most. The ability to predict and identify presence or absence of rejection was not affected by different serum creatinine values. Doppler US was significantly superior to MR imaging in identifying allograft rejection, demonstrating a higher sensitivity (95% vs. 70%), specificity (95% vs. 73%), and accuracy (95% vs. 71%). Because of its low cost and accessibility, Doppler US should become the primary modality for renal transplant screening.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

February 1987

Volume

162

Issue

2

Start / End Page

337 / 342

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Prospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Spectroscopy
  • Kidney Transplantation
  • Kidney
  • Humans
  • Graft Rejection
 

Citation

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Steinberg, H. V., Nelson, R. C., Murphy, F. B., Chezmar, J. L., Baumgartner, B. R., Delaney, V. B., … Bernardino, M. E. (1987). Renal allograft rejection: evaluation by Doppler US and MR imaging. Radiology, 162(2), 337–342. https://doi.org/10.1148/radiology.162.2.3541027
Steinberg, H. V., R. C. Nelson, F. B. Murphy, J. L. Chezmar, B. R. Baumgartner, V. B. Delaney, J. D. Whelchel, and M. E. Bernardino. “Renal allograft rejection: evaluation by Doppler US and MR imaging.Radiology 162, no. 2 (February 1987): 337–42. https://doi.org/10.1148/radiology.162.2.3541027.
Steinberg HV, Nelson RC, Murphy FB, Chezmar JL, Baumgartner BR, Delaney VB, et al. Renal allograft rejection: evaluation by Doppler US and MR imaging. Radiology. 1987 Feb;162(2):337–42.
Steinberg, H. V., et al. “Renal allograft rejection: evaluation by Doppler US and MR imaging.Radiology, vol. 162, no. 2, Feb. 1987, pp. 337–42. Pubmed, doi:10.1148/radiology.162.2.3541027.
Steinberg HV, Nelson RC, Murphy FB, Chezmar JL, Baumgartner BR, Delaney VB, Whelchel JD, Bernardino ME. Renal allograft rejection: evaluation by Doppler US and MR imaging. Radiology. 1987 Feb;162(2):337–342.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

February 1987

Volume

162

Issue

2

Start / End Page

337 / 342

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Prospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Spectroscopy
  • Kidney Transplantation
  • Kidney
  • Humans
  • Graft Rejection