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The role of apolipoprotein E in the nervous system.

Publication ,  Journal Article
Weisgraber, KH; Roses, AD; Strittmatter, WJ
Published in: Curr Opin Lipidol
April 1994

Human apolipoprotein (apo)E, an important component of plasma lipoprotein metabolism, was recently linked to Alzheimer's disease. Of the three common apoE alleles, epsilon 4 has emerged as a major risk factor. This review summarizes the data leading to this conclusion and discusses possible mechanisms for apoE involvement based on recent biochemical studies.

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Published In

Curr Opin Lipidol

DOI

ISSN

0957-9672

Publication Date

April 1994

Volume

5

Issue

2

Start / End Page

110 / 116

Location

England

Related Subject Headings

  • tau Proteins
  • Nervous System Physiological Phenomena
  • Humans
  • Cardiovascular System & Hematology
  • Apolipoproteins E
  • Alzheimer Disease
  • 3205 Medical biochemistry and metabolomics
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Weisgraber, K. H., Roses, A. D., & Strittmatter, W. J. (1994). The role of apolipoprotein E in the nervous system. Curr Opin Lipidol, 5(2), 110–116. https://doi.org/10.1097/00041433-199404000-00007
Weisgraber, K. H., A. D. Roses, and W. J. Strittmatter. “The role of apolipoprotein E in the nervous system.Curr Opin Lipidol 5, no. 2 (April 1994): 110–16. https://doi.org/10.1097/00041433-199404000-00007.
Weisgraber KH, Roses AD, Strittmatter WJ. The role of apolipoprotein E in the nervous system. Curr Opin Lipidol. 1994 Apr;5(2):110–6.
Weisgraber, K. H., et al. “The role of apolipoprotein E in the nervous system.Curr Opin Lipidol, vol. 5, no. 2, Apr. 1994, pp. 110–16. Pubmed, doi:10.1097/00041433-199404000-00007.
Weisgraber KH, Roses AD, Strittmatter WJ. The role of apolipoprotein E in the nervous system. Curr Opin Lipidol. 1994 Apr;5(2):110–116.

Published In

Curr Opin Lipidol

DOI

ISSN

0957-9672

Publication Date

April 1994

Volume

5

Issue

2

Start / End Page

110 / 116

Location

England

Related Subject Headings

  • tau Proteins
  • Nervous System Physiological Phenomena
  • Humans
  • Cardiovascular System & Hematology
  • Apolipoproteins E
  • Alzheimer Disease
  • 3205 Medical biochemistry and metabolomics
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology