A waiting time problem arising from the study of multi-stage carcinogenesis
Publication
, Journal Article
Durrett, R; Schmidt, D; Schweinsberg, J
Published in: Annals of Applied Probability
April 1, 2009
We consider the population genetics problem: how long does it take before some member of the population has m specified mutations? The case m = 2 is relevant to onset of cancer due to the inactivation of both copies of a tumor suppressor gene. Models for larger m are needed for colon cancer and other diseases where a sequence of mutations leads to cells with uncontrolled growth. © Institute of Mathematical Statistics, 2009.
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Published In
Annals of Applied Probability
DOI
EISSN
1050-5164
ISSN
1050-5164
Publication Date
April 1, 2009
Volume
19
Issue
2
Start / End Page
676 / 718
Related Subject Headings
- Statistics & Probability
- 4905 Statistics
- 4901 Applied mathematics
- 0104 Statistics
- 0102 Applied Mathematics
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Durrett, R., Schmidt, D., & Schweinsberg, J. (2009). A waiting time problem arising from the study of multi-stage carcinogenesis. Annals of Applied Probability, 19(2), 676–718. https://doi.org/10.1214/08-AAP559
Durrett, R., D. Schmidt, and J. Schweinsberg. “A waiting time problem arising from the study of multi-stage carcinogenesis.” Annals of Applied Probability 19, no. 2 (April 1, 2009): 676–718. https://doi.org/10.1214/08-AAP559.
Durrett R, Schmidt D, Schweinsberg J. A waiting time problem arising from the study of multi-stage carcinogenesis. Annals of Applied Probability. 2009 Apr 1;19(2):676–718.
Durrett, R., et al. “A waiting time problem arising from the study of multi-stage carcinogenesis.” Annals of Applied Probability, vol. 19, no. 2, Apr. 2009, pp. 676–718. Scopus, doi:10.1214/08-AAP559.
Durrett R, Schmidt D, Schweinsberg J. A waiting time problem arising from the study of multi-stage carcinogenesis. Annals of Applied Probability. 2009 Apr 1;19(2):676–718.
Published In
Annals of Applied Probability
DOI
EISSN
1050-5164
ISSN
1050-5164
Publication Date
April 1, 2009
Volume
19
Issue
2
Start / End Page
676 / 718
Related Subject Headings
- Statistics & Probability
- 4905 Statistics
- 4901 Applied mathematics
- 0104 Statistics
- 0102 Applied Mathematics