Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration.

Publication ,  Journal Article
Rubin, GD; Lane, MJ; Bloch, DA; Leung, AN; Stark, P
Published in: Radiology
December 1996

PURPOSE: To determine the effect of varying iodine concentration on arterial enhancement and perivenous artifact during thoracic spiral computed tomographic (CT) scanning. MATERIALS AND METHODS: One hundred thirty-eight outpatients received 15.0 g (n = 76) or 22.5 g (n = 62) of iodine (300 mg/mL iodine) while undergoing thoracic spiral CT. Patients received either undiluted contrast medium, 1:1 normal saline dilution, or 3:1 normal saline dilution. Contrast medium was injected at a flow rate determined to deliver the entire iodine dose within 40 seconds. Attenuation was measured within arteries and veins. Three blinded thoracic radiologists independently graded perivenous artifact and arterial enhancement. RESULTS: Perivenous artifacts were statistically significantly reduced with successive iodine dilution (P < .002). Arterial enhancement was statistically significantly better with 15.0 g of iodine diluted 1:1 when compared with the same iodine dose undiluted or diluted 3:1 (P < .01). Arterial enhancement achieved with 15.0 g of iodine diluted 1:1 was not statistically significantly lower than that achieved with 22.5 g of iodine diluted 1:1 (P > .31); however, venous artifact was greater with 22.5 g of iodine (P < .004). CONCLUSION: Reduced iodine concentration appears to diminish perivenous artifact and to result in improved arterial enhancement during thoracic spiral CT.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

December 1996

Volume

201

Issue

3

Start / End Page

785 / 791

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiography, Thoracic
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Iopamidol
  • Iodine
  • Humans
  • Contrast Media
  • Artifacts
  • Aged, 80 and over
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Rubin, G. D., Lane, M. J., Bloch, D. A., Leung, A. N., & Stark, P. (1996). Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration. Radiology, 201(3), 785–791. https://doi.org/10.1148/radiology.201.3.8939232
Rubin, G. D., M. J. Lane, D. A. Bloch, A. N. Leung, and P. Stark. “Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration.Radiology 201, no. 3 (December 1996): 785–91. https://doi.org/10.1148/radiology.201.3.8939232.
Rubin GD, Lane MJ, Bloch DA, Leung AN, Stark P. Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration. Radiology. 1996 Dec;201(3):785–91.
Rubin, G. D., et al. “Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration.Radiology, vol. 201, no. 3, Dec. 1996, pp. 785–91. Pubmed, doi:10.1148/radiology.201.3.8939232.
Rubin GD, Lane MJ, Bloch DA, Leung AN, Stark P. Optimization of thoracic spiral CT: effects of iodinated contrast medium concentration. Radiology. 1996 Dec;201(3):785–791.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

December 1996

Volume

201

Issue

3

Start / End Page

785 / 791

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiography, Thoracic
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Iopamidol
  • Iodine
  • Humans
  • Contrast Media
  • Artifacts
  • Aged, 80 and over