Regulation of CD8(+) T cell functions by RARgamma.
Publication
, Journal Article
Gordy, C; Dzhagalov, I; He, Y-W
Published in: Semin Immunol
February 2009
Retinoic acid plays a key role in the development and function of the immune system; however, the contribution of each of the three retinoic acid receptors (RARs) to the T cell immune response is not yet well understood. Of these receptors, both RARalpha and RARgamma are expressed in T lymphocytes. While possible functional redundancy thus complicates understanding of the role of each receptor in T cells, emerging data suggest that RARalpha and RARgamma function differently in thymocyte development and that RARgamma is required for both primary and secondary CD8(+) T cell immune responses.
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Published In
Semin Immunol
DOI
ISSN
1044-5323
Publication Date
February 2009
Volume
21
Issue
1
Start / End Page
2 / 7
Location
England
Related Subject Headings
- Tretinoin
- T-Lymphocyte Subsets
- Retinoic Acid Receptor gamma
- Receptors, Retinoic Acid
- Immunology
- Humans
- Gastrointestinal Tract
- CD8-Positive T-Lymphocytes
- Apoptosis
- Antineoplastic Agents
Citation
APA
Chicago
ICMJE
MLA
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Gordy, C., Dzhagalov, I., & He, Y.-W. (2009). Regulation of CD8(+) T cell functions by RARgamma. Semin Immunol, 21(1), 2–7. https://doi.org/10.1016/j.smim.2008.07.002
Gordy, Claire, Ivan Dzhagalov, and You-Wen He. “Regulation of CD8(+) T cell functions by RARgamma.” Semin Immunol 21, no. 1 (February 2009): 2–7. https://doi.org/10.1016/j.smim.2008.07.002.
Gordy C, Dzhagalov I, He Y-W. Regulation of CD8(+) T cell functions by RARgamma. Semin Immunol. 2009 Feb;21(1):2–7.
Gordy, Claire, et al. “Regulation of CD8(+) T cell functions by RARgamma.” Semin Immunol, vol. 21, no. 1, Feb. 2009, pp. 2–7. Pubmed, doi:10.1016/j.smim.2008.07.002.
Gordy C, Dzhagalov I, He Y-W. Regulation of CD8(+) T cell functions by RARgamma. Semin Immunol. 2009 Feb;21(1):2–7.
Published In
Semin Immunol
DOI
ISSN
1044-5323
Publication Date
February 2009
Volume
21
Issue
1
Start / End Page
2 / 7
Location
England
Related Subject Headings
- Tretinoin
- T-Lymphocyte Subsets
- Retinoic Acid Receptor gamma
- Receptors, Retinoic Acid
- Immunology
- Humans
- Gastrointestinal Tract
- CD8-Positive T-Lymphocytes
- Apoptosis
- Antineoplastic Agents