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Botulinum toxin for blepharospasm: single-fiber EMG studies.

Publication ,  Journal Article
Sanders, DB; Massey, EW; Buckley, EG
Published in: Neurology
April 1986

In four patients who received periocular injections of botulinum toxin for blepharospasm, abnormal neuromuscular transmission was demonstrated by single-fiber EMG in arm muscles. The time course with which the abnormalities developed and cleared, as well as the inverse relationship between the neuromuscular jitter and the firing rate in the abnormal muscles, indicated that the toxin caused the abnormalities in arm muscles. No weakness was detected clinically in muscles distant from the face, but the abnormal neuromuscular transmission indicates that the toxin spread remotely from the site of injection.

Duke Scholars

Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

April 1986

Volume

36

Issue

4

Start / End Page

545 / 547

Location

United States

Related Subject Headings

  • Neuromuscular Junction
  • Neurology & Neurosurgery
  • Muscles
  • Middle Aged
  • Humans
  • Female
  • Eyelid Diseases
  • Eye
  • Electromyography
  • Botulinum Toxins
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sanders, D. B., Massey, E. W., & Buckley, E. G. (1986). Botulinum toxin for blepharospasm: single-fiber EMG studies. Neurology, 36(4), 545–547. https://doi.org/10.1212/wnl.36.4.545
Sanders, D. B., E. W. Massey, and E. G. Buckley. “Botulinum toxin for blepharospasm: single-fiber EMG studies.Neurology 36, no. 4 (April 1986): 545–47. https://doi.org/10.1212/wnl.36.4.545.
Sanders DB, Massey EW, Buckley EG. Botulinum toxin for blepharospasm: single-fiber EMG studies. Neurology. 1986 Apr;36(4):545–7.
Sanders, D. B., et al. “Botulinum toxin for blepharospasm: single-fiber EMG studies.Neurology, vol. 36, no. 4, Apr. 1986, pp. 545–47. Pubmed, doi:10.1212/wnl.36.4.545.
Sanders DB, Massey EW, Buckley EG. Botulinum toxin for blepharospasm: single-fiber EMG studies. Neurology. 1986 Apr;36(4):545–547.

Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

April 1986

Volume

36

Issue

4

Start / End Page

545 / 547

Location

United States

Related Subject Headings

  • Neuromuscular Junction
  • Neurology & Neurosurgery
  • Muscles
  • Middle Aged
  • Humans
  • Female
  • Eyelid Diseases
  • Eye
  • Electromyography
  • Botulinum Toxins