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The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis.

Publication ,  Journal Article
Burns, TM; Grouse, CK; Wolfe, GI; Conaway, MR; Sanders, DB; MG Composite and MG-OL15 Study Group,
Published in: Muscle Nerve
January 2011

The MG-QOL15 is helpful in informing the clinician about the patient's perception of the extent of and dissatisfaction with myasthenia gravis (MG)-related dysfunction. The aims of this study were to determine the usefulness of the MG-QOL15 for following individuals with MG and to guide clinical researchers who plan to use the MG-QOL15. We assessed sensitivity and specificity for detecting clinical change and evaluated test-retest reliability. Sensitivities and specificities of various cut-points of change in scores are presented. Also presented are means and standard deviations of MG-QOL15 scores for all patients and for subgroups of patients. The test-retest reliability coefficient was 98.6%. The MG-QOL15 has an acceptable longitudinal construct validity. We consider this instrument to be most useful for informing the clinician about the patient's perception and tolerance of MG-related dysfunction. More objective measures, such as the MG Composite, should also be used to follow disease severity.

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Published In

Muscle Nerve

DOI

EISSN

1097-4598

Publication Date

January 2011

Volume

43

Issue

1

Start / End Page

14 / 18

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Quality of Life
  • Prospective Studies
  • Predictive Value of Tests
  • Neurology & Neurosurgery
  • Myasthenia Gravis
  • Mental Health
  • Humans
 

Citation

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Burns, T. M., Grouse, C. K., Wolfe, G. I., Conaway, M. R., Sanders, D. B., & MG Composite and MG-OL15 Study Group, . (2011). The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis. Muscle Nerve, 43(1), 14–18. https://doi.org/10.1002/mus.21883
Burns, Ted M., C. K. Grouse, Gil I. Wolfe, Mark R. Conaway, Donald B. Sanders, and Donald B. MG Composite and MG-OL15 Study Group. “The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis.Muscle Nerve 43, no. 1 (January 2011): 14–18. https://doi.org/10.1002/mus.21883.
Burns TM, Grouse CK, Wolfe GI, Conaway MR, Sanders DB, MG Composite and MG-OL15 Study Group. The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis. Muscle Nerve. 2011 Jan;43(1):14–8.
Burns, Ted M., et al. “The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis.Muscle Nerve, vol. 43, no. 1, Jan. 2011, pp. 14–18. Pubmed, doi:10.1002/mus.21883.
Burns TM, Grouse CK, Wolfe GI, Conaway MR, Sanders DB, MG Composite and MG-OL15 Study Group. The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis. Muscle Nerve. 2011 Jan;43(1):14–18.
Journal cover image

Published In

Muscle Nerve

DOI

EISSN

1097-4598

Publication Date

January 2011

Volume

43

Issue

1

Start / End Page

14 / 18

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Quality of Life
  • Prospective Studies
  • Predictive Value of Tests
  • Neurology & Neurosurgery
  • Myasthenia Gravis
  • Mental Health
  • Humans