Skip to main content
Journal cover image

Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest.

Publication ,  Journal Article
Aguila, A; Funderburk, M; Guler, A; McNitt, S; Hallinan, W; Daubert, JP; Delehanty, JM; Aktas, MK
Published in: Resuscitation
December 2010

INTRODUCTION: Therapeutic hypothermia has been shown to provide neuroprotection and improved survival in patients suffering a cardiac arrest. We report outcomes of consecutive patients receiving therapeutic hypothermia for cardiac arrest and describe predictors of short and long-term survival. METHODS: Eighty patients receiving therapeutic hypothermia between January 2005 and December 2008 were identified and categorized as those who survived and died. Outcomes and predictors of survival were determined. RESULTS: Forty-five patients (56%) survived to hospital discharge and were alive at 30 days and among survivors 41 (91%) were alive 1 year after discharge. Survivors were younger, were more likely to present with VF, required less epinephrine during resuscitation, were more likely to have preserved renal function, and were less likely to be taking beta-blockers and ACE inhibitors. Predictors of survival included VF on presentation (OR 14.9, CI 2.7-83.2, p=0.002), pre-cardiac arrest aspirin use (OR 9.7, CI 1.6-61.1, p=0.02), return of spontaneous circulation <20 min (OR 9.4, CI 2.2-41.1, p=0.003), absence of coronary artery disease (OR 5.3, CI 1.1-24.7, p=0.002) and preserved renal function. CONCLUSION: Therapeutic hypothermia is useful in the treatment of patients suffering a cardiac arrest. Several clinical factors may aid in predicting patients who are likely to survive after a cardiac arrest.

Duke Scholars

Published In

Resuscitation

DOI

EISSN

1873-1570

Publication Date

December 2010

Volume

81

Issue

12

Start / End Page

1621 / 1626

Location

Ireland

Related Subject Headings

  • Ventricular Fibrillation
  • Treatment Outcome
  • Prognosis
  • Middle Aged
  • Male
  • Hypothermia, Induced
  • Humans
  • Heart Arrest
  • Female
  • Emergency & Critical Care Medicine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Aguila, A., Funderburk, M., Guler, A., McNitt, S., Hallinan, W., Daubert, J. P., … Aktas, M. K. (2010). Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest. Resuscitation, 81(12), 1621–1626. https://doi.org/10.1016/j.resuscitation.2010.07.004
Aguila, Alian, Mathew Funderburk, Ahmet Guler, Scott McNitt, William Hallinan, James P. Daubert, Joseph M. Delehanty, and Mehmet K. Aktas. “Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest.Resuscitation 81, no. 12 (December 2010): 1621–26. https://doi.org/10.1016/j.resuscitation.2010.07.004.
Aguila A, Funderburk M, Guler A, McNitt S, Hallinan W, Daubert JP, et al. Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest. Resuscitation. 2010 Dec;81(12):1621–6.
Aguila, Alian, et al. “Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest.Resuscitation, vol. 81, no. 12, Dec. 2010, pp. 1621–26. Pubmed, doi:10.1016/j.resuscitation.2010.07.004.
Aguila A, Funderburk M, Guler A, McNitt S, Hallinan W, Daubert JP, Delehanty JM, Aktas MK. Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest. Resuscitation. 2010 Dec;81(12):1621–1626.
Journal cover image

Published In

Resuscitation

DOI

EISSN

1873-1570

Publication Date

December 2010

Volume

81

Issue

12

Start / End Page

1621 / 1626

Location

Ireland

Related Subject Headings

  • Ventricular Fibrillation
  • Treatment Outcome
  • Prognosis
  • Middle Aged
  • Male
  • Hypothermia, Induced
  • Humans
  • Heart Arrest
  • Female
  • Emergency & Critical Care Medicine