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Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation.

Publication ,  Journal Article
Parikh, SS; Jons, C; McNitt, S; Daubert, JP; Schwarz, KQ; Hall, B
Published in: Pacing Clin Electrophysiol
May 2010

BACKGROUND: Recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA) has been well established and is in part related to left atrial (LA) size. The purpose of this study was to assess the predictive capability of LA diameter (LAD) and LA volume (LAV) by echocardiography and computed tomography (CT) to determine success in patients undergoing RFCA of AF. METHODS: Eighty-eight patients with paroxysmal or persistent AF who had undergone RFCA and had a prior transthoracic echocardiogram (TTE), transesophageal echocardiogram (TEE), and CT were enrolled in the study. TTE LADs and LV ejection fraction as well as TEE LADs and LAVs in three views were recorded. CT LAVs were also recorded. Clinical parameters prior to ablation as well as at 1-year follow-up were assessed. RESULTS: A total of 40 (45%) patients with paroxysmal AF and 48 (55%) patients with persistent AF were analyzed. Paroxysmal AF patients had a RFCA success rate of 88% at 1 year with persistent AF patients having a 52% success rate (P < 0.001). A CT-derived LAV >or= 117 cc was associated with an odds ratio (OR) for recurrence of 4.8 (95% confidence interval [CI]=[1.4-16.4], P = 0.01) while a LAV >or=130 cc was associated with an OR for recurrence of 22.0 (95% CI =[2.5-191.0], P = 0.005) after adjustment for persistent AF. CONCLUSIONS: LA dimensions and AF type are highly predictive of AF recurrence following RFCA. LAV by CT has significant predictive benefit over standard LADs in severely enlarged atria even after adjustment for AF type.

Duke Scholars

Published In

Pacing Clin Electrophysiol

DOI

EISSN

1540-8159

Publication Date

May 2010

Volume

33

Issue

5

Start / End Page

532 / 540

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tomography, X-Ray Computed
  • Recurrence
  • Prognosis
  • Organ Size
  • Middle Aged
  • Male
  • Humans
  • Heart Atria
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Parikh, S. S., Jons, C., McNitt, S., Daubert, J. P., Schwarz, K. Q., & Hall, B. (2010). Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation. Pacing Clin Electrophysiol, 33(5), 532–540. https://doi.org/10.1111/j.1540-8159.2010.02693.x
Parikh, Sachin S., Christian Jons, Scott McNitt, James P. Daubert, Karl Q. Schwarz, and Burr Hall. “Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation.Pacing Clin Electrophysiol 33, no. 5 (May 2010): 532–40. https://doi.org/10.1111/j.1540-8159.2010.02693.x.
Parikh SS, Jons C, McNitt S, Daubert JP, Schwarz KQ, Hall B. Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation. Pacing Clin Electrophysiol. 2010 May;33(5):532–40.
Parikh, Sachin S., et al. “Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation.Pacing Clin Electrophysiol, vol. 33, no. 5, May 2010, pp. 532–40. Pubmed, doi:10.1111/j.1540-8159.2010.02693.x.
Parikh SS, Jons C, McNitt S, Daubert JP, Schwarz KQ, Hall B. Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation. Pacing Clin Electrophysiol. 2010 May;33(5):532–540.

Published In

Pacing Clin Electrophysiol

DOI

EISSN

1540-8159

Publication Date

May 2010

Volume

33

Issue

5

Start / End Page

532 / 540

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tomography, X-Ray Computed
  • Recurrence
  • Prognosis
  • Organ Size
  • Middle Aged
  • Male
  • Humans
  • Heart Atria
  • Female