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[Psychiatric and behavioral aspects of cardiovascular disease: epidemiology, mechanisms, and treatment].

Publication ,  Journal Article
Smith, PJ; Blumenthal, JA
Published in: Rev Esp Cardiol
October 2011

Psychosocial and behavioral factors, including mood (depression, anxiety, anger, and stress), personality (Type A, Type D, and hostility), and social support, are associated with both the development and progression of cardiovascular disease. "Negative" emotions have been associated with increased rates of cardiovascular death and recurrent cardiac events, although the mechanisms responsible for this association remain unclear. A number of pathophysiological mechanisms have been proposed to explain these relationships, including hypothalamic-pituitary-adrenal axis dysregulation, platelet activation, and inflammation. Behavioral factors also have been implicated, such as nonadherence to prescribed medical therapies and physical inactivity. Several randomized trials of patients with cardiovascular disease have examined the impact of pharmacologic and behavioral treatments on hard cardiovascular disease events as well as on cardiovascular disease biomarkers of risk. Although psychological treatments generally have been shown to improve quality of life and psychological functioning among cardiac patients, the benefit of psychological interventions with respect to improving clinical outcomes has not been conclusively demonstrated.

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Published In

Rev Esp Cardiol

DOI

EISSN

1579-2242

Publication Date

October 2011

Volume

64

Issue

10

Start / End Page

924 / 933

Location

Spain

Related Subject Headings

  • Type A Personality
  • Stress, Psychological
  • Socioeconomic Factors
  • Social Support
  • Personality
  • Mental Disorders
  • Humans
  • Hostility
  • Depression
  • Cardiovascular System & Hematology
 

Citation

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ICMJE
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Smith, P. J., & Blumenthal, J. A. (2011). [Psychiatric and behavioral aspects of cardiovascular disease: epidemiology, mechanisms, and treatment]. Rev Esp Cardiol, 64(10), 924–933. https://doi.org/10.1016/j.recesp.2011.06.003
Smith, Patrick J., and James A. Blumenthal. “[Psychiatric and behavioral aspects of cardiovascular disease: epidemiology, mechanisms, and treatment].Rev Esp Cardiol 64, no. 10 (October 2011): 924–33. https://doi.org/10.1016/j.recesp.2011.06.003.
Smith, Patrick J., and James A. Blumenthal. “[Psychiatric and behavioral aspects of cardiovascular disease: epidemiology, mechanisms, and treatment].Rev Esp Cardiol, vol. 64, no. 10, Oct. 2011, pp. 924–33. Pubmed, doi:10.1016/j.recesp.2011.06.003.

Published In

Rev Esp Cardiol

DOI

EISSN

1579-2242

Publication Date

October 2011

Volume

64

Issue

10

Start / End Page

924 / 933

Location

Spain

Related Subject Headings

  • Type A Personality
  • Stress, Psychological
  • Socioeconomic Factors
  • Social Support
  • Personality
  • Mental Disorders
  • Humans
  • Hostility
  • Depression
  • Cardiovascular System & Hematology