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The promise and potential challenges of intermittent preventive treatment for malaria in infants (IPTi).

Publication ,  Journal Article
O'Meara, WP; Breman, JG; McKenzie, FE
Published in: Malar J
July 20, 2005

Intermittent preventive treatment (IPT) administers a full therapeutic course of an anti-malarial drug at predetermined intervals, regardless of infection or disease status. It is recommended by the World Health Organization (WHO) for protecting pregnant women from the adverse effects of malaria (IPTp) and shows great potential as a strategy for reducing illness from malaria during infancy (IPTi). Administered concurrently with standard immunizations, IPTi is expected to reduce the frequency of clinical disease, but to allow blood-stage infections to occur between treatments, thus allowing parasite-specific immunity to develop. While wide deployment of IPTi is being considered, it is important to assess other potential effects. Transmission conditions, drug choice and administration schedule will likely affect the possibility of post-treatment rebound in child morbidity and mortality and the increased spread of parasite drug resistance and should be considered when implementing IPTi.

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Published In

Malar J

DOI

EISSN

1475-2875

Publication Date

July 20, 2005

Volume

4

Start / End Page

33

Location

England

Related Subject Headings

  • Tropical Medicine
  • Malaria
  • Infant
  • Humans
  • Drug Resistance
  • Antimalarials
  • Aging
  • 4206 Public health
  • 3207 Medical microbiology
  • 3107 Microbiology
 

Citation

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O’Meara, W. P., Breman, J. G., & McKenzie, F. E. (2005). The promise and potential challenges of intermittent preventive treatment for malaria in infants (IPTi). Malar J, 4, 33. https://doi.org/10.1186/1475-2875-4-33
O’Meara, Wendy Prudhomme, Joel G. Breman, and F Ellis McKenzie. “The promise and potential challenges of intermittent preventive treatment for malaria in infants (IPTi).Malar J 4 (July 20, 2005): 33. https://doi.org/10.1186/1475-2875-4-33.
O’Meara, Wendy Prudhomme, et al. “The promise and potential challenges of intermittent preventive treatment for malaria in infants (IPTi).Malar J, vol. 4, July 2005, p. 33. Pubmed, doi:10.1186/1475-2875-4-33.
Journal cover image

Published In

Malar J

DOI

EISSN

1475-2875

Publication Date

July 20, 2005

Volume

4

Start / End Page

33

Location

England

Related Subject Headings

  • Tropical Medicine
  • Malaria
  • Infant
  • Humans
  • Drug Resistance
  • Antimalarials
  • Aging
  • 4206 Public health
  • 3207 Medical microbiology
  • 3107 Microbiology