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Inappropriate antidiuretic hormone secretion. Occurrence in a patient with Rocky Mountain spotted fever.

Publication ,  Journal Article
Sexton, DJ; Clapp, J
Published in: Arch Intern Med
March 1977

A 51-year-old man with serologically confirmed Rocky Mountain spotted fever was believed to have inappropriate antidiuretic hormone (ADH) secretion. He was observed for four days in the hospital until the correct diagnosis was made. During this period, he progressively became more hyponatremic, despite a low BUN level and the administration of large amounts of sodium and water. At the time, his serum sodium concentration was 117 mEq/liter, and his urine was hypertonic to that of serum. Thereafter, his serum sodium level rose with fluid restriction. Rickettsia-induced CNS damage may have lead to the inappropriate ADH release that was observed in this patient.

Duke Scholars

Published In

Arch Intern Med

DOI

ISSN

0003-9926

Publication Date

March 1977

Volume

137

Issue

3

Start / End Page

362 / 363

Location

United States

Related Subject Headings

  • Vasopressins
  • Sodium
  • Rocky Mountain Spotted Fever
  • Middle Aged
  • Male
  • Hyponatremia
  • Humans
  • General & Internal Medicine
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences
 

Citation

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Sexton, D. J., & Clapp, J. (1977). Inappropriate antidiuretic hormone secretion. Occurrence in a patient with Rocky Mountain spotted fever. Arch Intern Med, 137(3), 362–363. https://doi.org/10.1001/archinte.137.3.362
Sexton, D. J., and J. Clapp. “Inappropriate antidiuretic hormone secretion. Occurrence in a patient with Rocky Mountain spotted fever.Arch Intern Med 137, no. 3 (March 1977): 362–63. https://doi.org/10.1001/archinte.137.3.362.
Sexton, D. J., and J. Clapp. “Inappropriate antidiuretic hormone secretion. Occurrence in a patient with Rocky Mountain spotted fever.Arch Intern Med, vol. 137, no. 3, Mar. 1977, pp. 362–63. Pubmed, doi:10.1001/archinte.137.3.362.

Published In

Arch Intern Med

DOI

ISSN

0003-9926

Publication Date

March 1977

Volume

137

Issue

3

Start / End Page

362 / 363

Location

United States

Related Subject Headings

  • Vasopressins
  • Sodium
  • Rocky Mountain Spotted Fever
  • Middle Aged
  • Male
  • Hyponatremia
  • Humans
  • General & Internal Medicine
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences