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Morphological studies of the murine heart based on probabilistic and statistical atlases.

Publication ,  Journal Article
Perperidis, D; Bucholz, E; Johnson, GA; Constantinides, C
Published in: Comput Med Imaging Graph
March 2012
Published version (DOI) Link to item

This study directly compares morphological features of the mouse heart in its end-relaxed state based on constructed morphometric maps and atlases using principal component analysis in C57BL/6J (n=8) and DBA (n=5) mice. In probabilistic atlases, a gradient probability exists for both strains in longitudinal locations from base to apex. Based on the statistical atlases, differences in size (49.8%), apical direction (15.6%), basal ventricular blood pool size (13.2%), and papillary muscle shape and position (17.2%) account for the most significant modes of shape variability for the left ventricle of the C57BL/6J mice. For DBA mice, differences in left ventricular size and direction (67.4%), basal size (15.7%), and position of papillary muscles (16.8%) account for significant variability.

Duke Scholars

Elizabeth K Bucholz
Author Elizabeth K Bucholz Biomedical Engineering
G. Allan Johnson
Author G. Allan Johnson Radiology

Published In

Comput Med Imaging Graph

DOI

10.1016/j.compmedimag.2011.07.001

EISSN

1879-0771

Publication Date

March 2012

Volume

36

Issue

2

Start / End Page

119 / 129

Location

United States

Related Subject Headings

  • Subtraction Technique
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Mice, Inbred C57BL
  • Mice
  • Male
  • Magnetic Resonance Imaging
  • Image Interpretation, Computer-Assisted
  • Image Enhancement
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Perperidis, D., Bucholz, E., Johnson, G. A., & Constantinides, C. (2012). Morphological studies of the murine heart based on probabilistic and statistical atlases. Comput Med Imaging Graph, 36(2), 119–129. https://doi.org/10.1016/j.compmedimag.2011.07.001
Perperidis, Dimitrios, Elizabeth Bucholz, G Allan Johnson, and Christakis Constantinides. “Morphological studies of the murine heart based on probabilistic and statistical atlases.” Comput Med Imaging Graph 36, no. 2 (March 2012): 119–29. https://doi.org/10.1016/j.compmedimag.2011.07.001.
Perperidis D, Bucholz E, Johnson GA, Constantinides C. Morphological studies of the murine heart based on probabilistic and statistical atlases. Comput Med Imaging Graph. 2012 Mar;36(2):119–29.
Perperidis, Dimitrios, et al. “Morphological studies of the murine heart based on probabilistic and statistical atlases.” Comput Med Imaging Graph, vol. 36, no. 2, Mar. 2012, pp. 119–29. Pubmed, doi:10.1016/j.compmedimag.2011.07.001.
Perperidis D, Bucholz E, Johnson GA, Constantinides C. Morphological studies of the murine heart based on probabilistic and statistical atlases. Comput Med Imaging Graph. 2012 Mar;36(2):119–129.
Journal cover image

Published In

Comput Med Imaging Graph

DOI

10.1016/j.compmedimag.2011.07.001

EISSN

1879-0771

Publication Date

March 2012

Volume

36

Issue

2

Start / End Page

119 / 129

Location

United States

Related Subject Headings

  • Subtraction Technique
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Mice, Inbred C57BL
  • Mice
  • Male
  • Magnetic Resonance Imaging
  • Image Interpretation, Computer-Assisted
  • Image Enhancement