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Adequacy of urine cytology specimens: an assessment of collection techniques.

Publication ,  Journal Article
Hundley, AF; Maygarden, S; Wu, JM; Visco, AG; Connolly, A
Published in: Int Urogynecol J Pelvic Floor Dysfunct
September 2007

The objective of this study was to determine whether the method of urine collection impacts the adequacy and cell counts of cytology specimens in a low-risk population. Voided, post-cystometrogram (CMG), and bladder irrigant specimens were collected and evaluated for cytologic adequacy and average cell count by a single cytopathologist masked to the source of each sample. Data were analyzed to detect differences in specimen adequacy and cell counts based on method of collection. Both the voided and post-CMG specimens (97.3%, 93.7% respectively) were significantly more likely to be adequate compared to the bladder irrigant specimen (11.7%, p < 0.0001). The spontaneously voided specimen (211.4 +/- 100.1) had significantly higher cell counts than both the post-CMG specimen (85.9 +/- 86.6) and the cystoscopy specimen (6.4 +/- 19.6, p < 0.0001). In a multivariate linear model, collection method and specimen adequacy were associated with increased cell count/hpf (p < 0.001), as was the presence of hematuria on urine dipstick (p = 0.03). No cytologic abnormalities were diagnosed. Whereas both spontaneously voided and post-CMG specimens were consistently adequate for interpretation, spontaneous voided specimens were optimal with regard to maximizing cell count/hpf.

Duke Scholars

Published In

Int Urogynecol J Pelvic Floor Dysfunct

DOI

Publication Date

September 2007

Volume

18

Issue

9

Start / End Page

997 / 1001

Location

England

Related Subject Headings

  • Urine
  • Specimen Handling
  • Obstetrics & Reproductive Medicine
  • Multivariate Analysis
  • Middle Aged
  • Linear Models
  • Humans
  • Female
  • Cytological Techniques
  • Cystoscopy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hundley, A. F., Maygarden, S., Wu, J. M., Visco, A. G., & Connolly, A. (2007). Adequacy of urine cytology specimens: an assessment of collection techniques. Int Urogynecol J Pelvic Floor Dysfunct, 18(9), 997–1001. https://doi.org/10.1007/s00192-006-0277-5
Hundley, Andrew F., Susan Maygarden, Jennifer M. Wu, Anthony G. Visco, and AnnaMarie Connolly. “Adequacy of urine cytology specimens: an assessment of collection techniques.Int Urogynecol J Pelvic Floor Dysfunct 18, no. 9 (September 2007): 997–1001. https://doi.org/10.1007/s00192-006-0277-5.
Hundley AF, Maygarden S, Wu JM, Visco AG, Connolly A. Adequacy of urine cytology specimens: an assessment of collection techniques. Int Urogynecol J Pelvic Floor Dysfunct. 2007 Sep;18(9):997–1001.
Hundley, Andrew F., et al. “Adequacy of urine cytology specimens: an assessment of collection techniques.Int Urogynecol J Pelvic Floor Dysfunct, vol. 18, no. 9, Sept. 2007, pp. 997–1001. Pubmed, doi:10.1007/s00192-006-0277-5.
Hundley AF, Maygarden S, Wu JM, Visco AG, Connolly A. Adequacy of urine cytology specimens: an assessment of collection techniques. Int Urogynecol J Pelvic Floor Dysfunct. 2007 Sep;18(9):997–1001.

Published In

Int Urogynecol J Pelvic Floor Dysfunct

DOI

Publication Date

September 2007

Volume

18

Issue

9

Start / End Page

997 / 1001

Location

England

Related Subject Headings

  • Urine
  • Specimen Handling
  • Obstetrics & Reproductive Medicine
  • Multivariate Analysis
  • Middle Aged
  • Linear Models
  • Humans
  • Female
  • Cytological Techniques
  • Cystoscopy