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Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis.

Publication ,  Journal Article
Routh, JC; Pennison, M; Rosoklija, I; Dobbins, S; Kokorowski, PJ; Hubert, KC; Huang, L; Nelson, CP
Published in: J Urol
December 2011

PURPOSE: We have previously shown that nonwhite patients with ureteropelvic junction obstruction undergo pyeloplasty at a younger age than white patients. The mechanisms behind this finding are unclear, since there is no known racial variation in the natural history of ureteropelvic junction obstruction. We used a detailed clinical database to explain this phenomenon. MATERIALS AND METHODS: We retrospectively reviewed all patients undergoing primary pyeloplasty at our institution between 1992 and 2008. More than 360 data points were abstracted for each patient, including self-reported race, socioeconomic status, symptom duration and presentation. RESULTS: Of 847 patients undergoing pyeloplasty during the study period 741 met inclusion criteria. Nonwhite patients underwent surgery at a younger age (0.6 years) than whites (2.6 years, p <0.0001). When stratified by timing of clinical presentation (prenatal vs postnatal), there was no significant difference in race among patients presenting prenatally (0.37 vs 0.36 years, p = 0.22). Nonwhite patients presenting postnatally were significantly younger than white patients (6.3 vs 8.2 years, p = 0.03). This finding appeared to be due to differences in age at initial clinical presentation (5.4 vs 7.0 years, p = 0.03) and in time from initial clinical presentation to urological evaluation (0.6 vs 3.2 months, p = 0.03). These differences persisted after correcting for other factors, including markers of socioeconomic status. CONCLUSIONS: Consistent with previous studies, we found that nonwhite patients underwent primary pyeloplasty at a younger age than whites. This difference is limited to patients presenting after birth. Prenatally diagnosed patients underwent surgery at similar ages regardless of race.

Duke Scholars

Published In

J Urol

DOI

EISSN

1527-3792

Publication Date

December 2011

Volume

186

Issue

6

Start / End Page

2386 / 2391

Location

United States

Related Subject Headings

  • White People
  • Urology & Nephrology
  • Ureteral Obstruction
  • Time Factors
  • Retrospective Studies
  • Prenatal Diagnosis
  • Male
  • Kidney Pelvis
  • Infant
  • Humans
 

Citation

APA
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ICMJE
MLA
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Routh, J. C., Pennison, M., Rosoklija, I., Dobbins, S., Kokorowski, P. J., Hubert, K. C., … Nelson, C. P. (2011). Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis. J Urol, 186(6), 2386–2391. https://doi.org/10.1016/j.juro.2011.07.111
Routh, Jonathan C., Melanie Pennison, Ilina Rosoklija, Sarah Dobbins, Paul J. Kokorowski, Katherine C. Hubert, Lin Huang, and Caleb P. Nelson. “Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis.J Urol 186, no. 6 (December 2011): 2386–91. https://doi.org/10.1016/j.juro.2011.07.111.
Routh JC, Pennison M, Rosoklija I, Dobbins S, Kokorowski PJ, Hubert KC, et al. Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis. J Urol. 2011 Dec;186(6):2386–91.
Routh, Jonathan C., et al. “Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis.J Urol, vol. 186, no. 6, Dec. 2011, pp. 2386–91. Pubmed, doi:10.1016/j.juro.2011.07.111.
Routh JC, Pennison M, Rosoklija I, Dobbins S, Kokorowski PJ, Hubert KC, Huang L, Nelson CP. Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis. J Urol. 2011 Dec;186(6):2386–2391.
Journal cover image

Published In

J Urol

DOI

EISSN

1527-3792

Publication Date

December 2011

Volume

186

Issue

6

Start / End Page

2386 / 2391

Location

United States

Related Subject Headings

  • White People
  • Urology & Nephrology
  • Ureteral Obstruction
  • Time Factors
  • Retrospective Studies
  • Prenatal Diagnosis
  • Male
  • Kidney Pelvis
  • Infant
  • Humans