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Vesicoureteral reflux: current trends in diagnosis, screening, and treatment.
CONTEXT: Vesicoureteral reflux (VUR) is present in approximately 1% of children in North America and Europe and is associated with an increased risk of pyelonephritis and renal scarring. Despite its prevalence and potential morbidity, however, many aspects of VUR management are controversial. OBJECTIVE: Review the evidence surrounding current controversies in VUR diagnosis, screening, and treatment. EVIDENCE ACQUISITION: A systematic review was performed of Medline, Embase, Prospero, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, clinicaltrials.gov, and the most recent guidelines of relevant medical specialty organizations. EVIDENCE SYNTHESIS: We objectively assessed and summarized the published data, focusing on recent areas of controversy relating to VUR screening, diagnosis, and treatment. CONCLUSIONS: The evidence base for many current management patterns in VUR is limited. Areas that could significantly benefit from additional future research include improved identification of children who are at risk for VUR-related renal morbidity, improved stratification tools for determining which children would benefit most from which VUR treatment option, and improved reporting of long-term outcomes of VUR treatments.
Duke Scholars
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Related Subject Headings
- Vesico-Ureteral Reflux
- Urology & Nephrology
- Treatment Outcome
- Predictive Value of Tests
- Practice Guidelines as Topic
- Mass Screening
- Infant
- Humans
- Evidence-Based Medicine
- Diagnostic Techniques, Urological
Citation
![Journal cover image](https://secure.syndetics.com/index.aspx?isbn=/lc.gif&issn=1873-7560&client=dukeuniv)
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Vesico-Ureteral Reflux
- Urology & Nephrology
- Treatment Outcome
- Predictive Value of Tests
- Practice Guidelines as Topic
- Mass Screening
- Infant
- Humans
- Evidence-Based Medicine
- Diagnostic Techniques, Urological