Skip to main content
Journal cover image

Abnormal brain activity related to performance monitoring and error detection in children with ADHD.

Publication ,  Journal Article
Liotti, M; Pliszka, SR; Perez, R; Kothmann, D; Woldorff, MG
Published in: Cortex
June 2005

Brain electrical activity associated with inhibitory control was recorded in ten ADHD and ten healthy children using high density event related potentials (ERPs) during the Stop Signal Task (SST). SST is a two-choice reaction time (RT) paradigm, in which subjects are required, on 25% of the trials, to withdraw their response upon presentation of a "Stop Signal". In the healthy children, the ERP evoked by the Stop Signal differed for successful inhibitions (SI) compared to failed inhibitions (FI), with greater amplitude of a positive wave peaking around 320 msec over anterior medial frontal scalp (P3a). Such success-related P3a activity was significantly reduced in amplitude in the ADHD group. In addition, the error related negativity (ERN), a sharp negative wave that is present selectively on error trials in choice RT experiments, peaking 100 ms after motor onset, and distributed over anterior medial frontal scalp, was also markedly reduced in the ADHD group. The scalp distribution of the group differences in P3a and the ERN is consistent with a reduction of activity of sources in dorsal anterior cingulate cortex (dACC), suggesting a global deficit in cognitive control operations subserved by dACC in ADHD.

Duke Scholars

Published In

Cortex

DOI

ISSN

0010-9452

Publication Date

June 2005

Volume

41

Issue

3

Start / End Page

377 / 388

Location

Italy

Related Subject Headings

  • Signal Detection, Psychological
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Gyrus Cinguli
  • Experimental Psychology
  • Evoked Potentials
  • Electroencephalography
  • Child
  • Brain
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Liotti, M., Pliszka, S. R., Perez, R., Kothmann, D., & Woldorff, M. G. (2005). Abnormal brain activity related to performance monitoring and error detection in children with ADHD. Cortex, 41(3), 377–388. https://doi.org/10.1016/s0010-9452(08)70274-0
Liotti, Mario, Steven R. Pliszka, Ricardo Perez, Delia Kothmann, and Marty G. Woldorff. “Abnormal brain activity related to performance monitoring and error detection in children with ADHD.Cortex 41, no. 3 (June 2005): 377–88. https://doi.org/10.1016/s0010-9452(08)70274-0.
Liotti M, Pliszka SR, Perez R, Kothmann D, Woldorff MG. Abnormal brain activity related to performance monitoring and error detection in children with ADHD. Cortex. 2005 Jun;41(3):377–88.
Liotti, Mario, et al. “Abnormal brain activity related to performance monitoring and error detection in children with ADHD.Cortex, vol. 41, no. 3, June 2005, pp. 377–88. Pubmed, doi:10.1016/s0010-9452(08)70274-0.
Liotti M, Pliszka SR, Perez R, Kothmann D, Woldorff MG. Abnormal brain activity related to performance monitoring and error detection in children with ADHD. Cortex. 2005 Jun;41(3):377–388.
Journal cover image

Published In

Cortex

DOI

ISSN

0010-9452

Publication Date

June 2005

Volume

41

Issue

3

Start / End Page

377 / 388

Location

Italy

Related Subject Headings

  • Signal Detection, Psychological
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Gyrus Cinguli
  • Experimental Psychology
  • Evoked Potentials
  • Electroencephalography
  • Child
  • Brain