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Assessment of retrograde cardioplegia distribution using contrast echocardiography.

Publication ,  Journal Article
Aronson, S; Lee, BK; Liddicoat, JR; Wiencek, JG; Feinstein, SB; Ellis, JE; Roizen, MF; Karp, RB
Published in: Ann Thorac Surg
October 1991

Retrograde cardioplegia has gained popularity in coronary and noncoronary cardiac operations. We have used contrast echocardiography in the open-chest canine model to compare the distribution of cardioplegia delivered antegrade in the aortic root versus retrograde through the coronary sinus, and to determine the effect of coronary occlusion on that delivery. With no coronary occlusion, antegrade cardioplegia was distributed to the entire left ventricle and septum whereas retrograde cardioplegia was distributed to the left ventricular free wall but had inconsistent delivery to the septum. Acute occlusion of the left circumflex coronary artery resulted in 57.06% +/- 9.52% of the left ventricle not being perfused by antegrade cardioplegia and occlusion of both the left circumflex and anterior descending coronary arteries caused a 65.46% +/- 18.5% reduction in perfusion by antegrade cardioplegia. Acute coronary occlusion had no effect on retrograde cardioplegia distribution. We conclude that retrograde cardioplegia is less homogeneous than antegrade cardioplegia in the intact coronary circulation but that retrograde cardioplegia preserves cardioplegia distal to acutely occluded coronary arteries. Furthermore, contrast echocardiography is a useful method of assessing myocardial perfusion and may have useful clinical applications.

Duke Scholars

Published In

Ann Thorac Surg

DOI

ISSN

0003-4975

Publication Date

October 1991

Volume

52

Issue

4

Start / End Page

810 / 814

Location

Netherlands

Related Subject Headings

  • Respiratory System
  • Echocardiography
  • Dogs
  • Coronary Vessels
  • Coronary Circulation
  • Contrast Media
  • Constriction
  • Cardioplegic Solutions
  • Aorta
  • Animals
 

Citation

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ICMJE
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Aronson, S., Lee, B. K., Liddicoat, J. R., Wiencek, J. G., Feinstein, S. B., Ellis, J. E., … Karp, R. B. (1991). Assessment of retrograde cardioplegia distribution using contrast echocardiography. Ann Thorac Surg, 52(4), 810–814. https://doi.org/10.1016/0003-4975(91)91216-i
Aronson, S., B. K. Lee, J. R. Liddicoat, J. G. Wiencek, S. B. Feinstein, J. E. Ellis, M. F. Roizen, and R. B. Karp. “Assessment of retrograde cardioplegia distribution using contrast echocardiography.Ann Thorac Surg 52, no. 4 (October 1991): 810–14. https://doi.org/10.1016/0003-4975(91)91216-i.
Aronson S, Lee BK, Liddicoat JR, Wiencek JG, Feinstein SB, Ellis JE, et al. Assessment of retrograde cardioplegia distribution using contrast echocardiography. Ann Thorac Surg. 1991 Oct;52(4):810–4.
Aronson, S., et al. “Assessment of retrograde cardioplegia distribution using contrast echocardiography.Ann Thorac Surg, vol. 52, no. 4, Oct. 1991, pp. 810–14. Pubmed, doi:10.1016/0003-4975(91)91216-i.
Aronson S, Lee BK, Liddicoat JR, Wiencek JG, Feinstein SB, Ellis JE, Roizen MF, Karp RB. Assessment of retrograde cardioplegia distribution using contrast echocardiography. Ann Thorac Surg. 1991 Oct;52(4):810–814.
Journal cover image

Published In

Ann Thorac Surg

DOI

ISSN

0003-4975

Publication Date

October 1991

Volume

52

Issue

4

Start / End Page

810 / 814

Location

Netherlands

Related Subject Headings

  • Respiratory System
  • Echocardiography
  • Dogs
  • Coronary Vessels
  • Coronary Circulation
  • Contrast Media
  • Constriction
  • Cardioplegic Solutions
  • Aorta
  • Animals