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Electron-Tunneling Pathways in Ruthenated Proteins

Publication ,  Journal Article
Beratan, DN; Nelson Onuchic, J; Betts, JN; Bowler, BE; Gray, HB
Published in: Journal of the American Chemical Society
January 1, 1990

We implement a numerical algorithm to survey proteins for electron-tunneling pathways. Insight is gained into the nature of the mediation process in long-distance electron-transfer reactions. The dominance of covalent and hydrogen bond pathways is shown. The method predicts the relative electronic couplings in ruthenated myoglobin and cytochrome c consistent with measured electron-transfer rates. It also allows the design of long-range electron-transfer systems. Qualitative differences between pathways arise from the protein secondary structure. Effects of this sort are not predicted from simpler models that neglect various details of the protein electronic structure. © 1990, American Chemical Society. All rights reserved.

Duke Scholars

Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

January 1, 1990

Volume

112

Issue

22

Start / End Page

7915 / 7921

Related Subject Headings

  • General Chemistry
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences
 

Citation

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Beratan, D. N., Nelson Onuchic, J., Betts, J. N., Bowler, B. E., & Gray, H. B. (1990). Electron-Tunneling Pathways in Ruthenated Proteins. Journal of the American Chemical Society, 112(22), 7915–7921. https://doi.org/10.1021/ja00178a011
Beratan, D. N., J. Nelson Onuchic, J. N. Betts, B. E. Bowler, and H. B. Gray. “Electron-Tunneling Pathways in Ruthenated Proteins.” Journal of the American Chemical Society 112, no. 22 (January 1, 1990): 7915–21. https://doi.org/10.1021/ja00178a011.
Beratan DN, Nelson Onuchic J, Betts JN, Bowler BE, Gray HB. Electron-Tunneling Pathways in Ruthenated Proteins. Journal of the American Chemical Society. 1990 Jan 1;112(22):7915–21.
Beratan, D. N., et al. “Electron-Tunneling Pathways in Ruthenated Proteins.” Journal of the American Chemical Society, vol. 112, no. 22, Jan. 1990, pp. 7915–21. Scopus, doi:10.1021/ja00178a011.
Beratan DN, Nelson Onuchic J, Betts JN, Bowler BE, Gray HB. Electron-Tunneling Pathways in Ruthenated Proteins. Journal of the American Chemical Society. 1990 Jan 1;112(22):7915–7921.
Journal cover image

Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

January 1, 1990

Volume

112

Issue

22

Start / End Page

7915 / 7921

Related Subject Headings

  • General Chemistry
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences