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Reduction in oocyte number following prenatal exposure to a diet high in galactose.

Publication ,  Journal Article
Chen, YT; Mattison, DR; Feigenbaum, L; Fukui, H; Schulman, JD
Published in: Science (New York, N.Y.)
December 1981

When pregnant rats were fed a 50 percent galactose diet there was a striking reduction in oocyte number in the offspring. The most prominent effects were noted after exposure to galactose during the premeiotic stages of oogenesis. Prenatal exposure to galactose or its metabolites may contribute to the premature ovarian failure characteristic of human galactosemia.

Duke Scholars

Published In

Science (New York, N.Y.)

DOI

EISSN

1095-9203

ISSN

0036-8075

Publication Date

December 1981

Volume

214

Issue

4525

Start / End Page

1145 / 1147

Related Subject Headings

  • Rats, Inbred Strains
  • Rats
  • Pregnancy
  • Ovum
  • Oocytes
  • Maternal-Fetal Exchange
  • General Science & Technology
  • Galactose
  • Fetus
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chen, Y. T., Mattison, D. R., Feigenbaum, L., Fukui, H., & Schulman, J. D. (1981). Reduction in oocyte number following prenatal exposure to a diet high in galactose. Science (New York, N.Y.), 214(4525), 1145–1147. https://doi.org/10.1126/science.7302587
Chen, Y. T., D. R. Mattison, L. Feigenbaum, H. Fukui, and J. D. Schulman. “Reduction in oocyte number following prenatal exposure to a diet high in galactose.Science (New York, N.Y.) 214, no. 4525 (December 1981): 1145–47. https://doi.org/10.1126/science.7302587.
Chen YT, Mattison DR, Feigenbaum L, Fukui H, Schulman JD. Reduction in oocyte number following prenatal exposure to a diet high in galactose. Science (New York, NY). 1981 Dec;214(4525):1145–7.
Chen, Y. T., et al. “Reduction in oocyte number following prenatal exposure to a diet high in galactose.Science (New York, N.Y.), vol. 214, no. 4525, Dec. 1981, pp. 1145–47. Epmc, doi:10.1126/science.7302587.
Chen YT, Mattison DR, Feigenbaum L, Fukui H, Schulman JD. Reduction in oocyte number following prenatal exposure to a diet high in galactose. Science (New York, NY). 1981 Dec;214(4525):1145–1147.
Journal cover image

Published In

Science (New York, N.Y.)

DOI

EISSN

1095-9203

ISSN

0036-8075

Publication Date

December 1981

Volume

214

Issue

4525

Start / End Page

1145 / 1147

Related Subject Headings

  • Rats, Inbred Strains
  • Rats
  • Pregnancy
  • Ovum
  • Oocytes
  • Maternal-Fetal Exchange
  • General Science & Technology
  • Galactose
  • Fetus
  • Female