Skip to main content
release_alert
Welcome to the new Scholars 3.0! Read about new features and let us know what you think.
cancel
Journal cover image

Efficacy and safety of nesiritide in patients with acute decompensated heart failure.

Publication ,  Journal Article
DeWald, TA; Hernandez, AF
Published in: Expert Rev Cardiovasc Ther
February 2010

Acute decompensated heart failure is a common clinical problem with associated poor outcomes. Over the last decade, attention to this area has greatly increased, with a focus on medical therapies that may safely offer improvement in acute symptoms and early outcomes. Previous therapies that focused on increased inotropy have generally failed to improve symptoms without adverse consequences. Thus, attention towards vasodilators and natriuretic peptides, such as nesiritide, has increased owing to nesiritide's symptomatic improvement and unique mechanism of improvement in hemodynamics. However, the pathophysiology of acute decompensated heart failure is complex and the impact of nesiritide on important clinical end points, beyond symptomatic and hemodynamic improvement, is unknown.

Duke Scholars

Published In

Expert Rev Cardiovasc Ther

DOI

EISSN

1744-8344

Publication Date

February 2010

Volume

8

Issue

2

Start / End Page

159 / 169

Location

England

Related Subject Headings

  • Vasodilator Agents
  • Natriuretic Peptide, Brain
  • Natriuretic Agents
  • Humans
  • Heart Failure
  • Cardiovascular System & Hematology
  • Acute Disease
  • 1117 Public Health and Health Services
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
DeWald, T. A., & Hernandez, A. F. (2010). Efficacy and safety of nesiritide in patients with acute decompensated heart failure. Expert Rev Cardiovasc Ther, 8(2), 159–169. https://doi.org/10.1586/erc.09.173
DeWald, Tracy A., and Adrian F. Hernandez. “Efficacy and safety of nesiritide in patients with acute decompensated heart failure.Expert Rev Cardiovasc Ther 8, no. 2 (February 2010): 159–69. https://doi.org/10.1586/erc.09.173.
DeWald TA, Hernandez AF. Efficacy and safety of nesiritide in patients with acute decompensated heart failure. Expert Rev Cardiovasc Ther. 2010 Feb;8(2):159–69.
DeWald, Tracy A., and Adrian F. Hernandez. “Efficacy and safety of nesiritide in patients with acute decompensated heart failure.Expert Rev Cardiovasc Ther, vol. 8, no. 2, Feb. 2010, pp. 159–69. Pubmed, doi:10.1586/erc.09.173.
DeWald TA, Hernandez AF. Efficacy and safety of nesiritide in patients with acute decompensated heart failure. Expert Rev Cardiovasc Ther. 2010 Feb;8(2):159–169.
Journal cover image

Published In

Expert Rev Cardiovasc Ther

DOI

EISSN

1744-8344

Publication Date

February 2010

Volume

8

Issue

2

Start / End Page

159 / 169

Location

England

Related Subject Headings

  • Vasodilator Agents
  • Natriuretic Peptide, Brain
  • Natriuretic Agents
  • Humans
  • Heart Failure
  • Cardiovascular System & Hematology
  • Acute Disease
  • 1117 Public Health and Health Services
  • 1102 Cardiorespiratory Medicine and Haematology