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Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes.

Publication ,  Journal Article
Petes, TD
Published in: Cell
March 1980

Recombinant DNA procedures and the yeast transformation technique were used to insert the yeast gene LEU 2 (coding for beta-isopropylmalate dehydrogenase) into the tandem array of ribosomal DNA genes of the yeast Saccharomyces cerevisiae. These insertions were shown by genetic and physical techniques to be unstable in meiosis. The meiotic instability was found to be the result of a high level of unequal recombination between ribosomal DNA gene clusters located on sister chromatids.

Duke Scholars

Published In

Cell

DOI

ISSN

0092-8674

Publication Date

March 1980

Volume

19

Issue

3

Start / End Page

765 / 774

Location

United States

Related Subject Headings

  • Transformation, Genetic
  • Saccharomyces cerevisiae
  • Recombination, Genetic
  • RNA, Ribosomal
  • Plasmids
  • Genes
  • Developmental Biology
  • DNA, Recombinant
  • DNA, Fungal
  • Chromosome Mapping
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Petes, T. D. (1980). Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. Cell, 19(3), 765–774. https://doi.org/10.1016/s0092-8674(80)80052-3
Petes, T. D. “Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes.Cell 19, no. 3 (March 1980): 765–74. https://doi.org/10.1016/s0092-8674(80)80052-3.
Petes, T. D. “Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes.Cell, vol. 19, no. 3, Mar. 1980, pp. 765–74. Pubmed, doi:10.1016/s0092-8674(80)80052-3.
Journal cover image

Published In

Cell

DOI

ISSN

0092-8674

Publication Date

March 1980

Volume

19

Issue

3

Start / End Page

765 / 774

Location

United States

Related Subject Headings

  • Transformation, Genetic
  • Saccharomyces cerevisiae
  • Recombination, Genetic
  • RNA, Ribosomal
  • Plasmids
  • Genes
  • Developmental Biology
  • DNA, Recombinant
  • DNA, Fungal
  • Chromosome Mapping