Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes.
Publication
, Journal Article
Petes, TD
Published in: Cell
March 1980
Recombinant DNA procedures and the yeast transformation technique were used to insert the yeast gene LEU 2 (coding for beta-isopropylmalate dehydrogenase) into the tandem array of ribosomal DNA genes of the yeast Saccharomyces cerevisiae. These insertions were shown by genetic and physical techniques to be unstable in meiosis. The meiotic instability was found to be the result of a high level of unequal recombination between ribosomal DNA gene clusters located on sister chromatids.
Duke Scholars
Published In
Cell
DOI
ISSN
0092-8674
Publication Date
March 1980
Volume
19
Issue
3
Start / End Page
765 / 774
Location
United States
Related Subject Headings
- Transformation, Genetic
- Saccharomyces cerevisiae
- Recombination, Genetic
- RNA, Ribosomal
- Plasmids
- Genes
- Developmental Biology
- DNA, Recombinant
- DNA, Fungal
- Chromosome Mapping
Citation
APA
Chicago
ICMJE
MLA
NLM
Petes, T. D. (1980). Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. Cell, 19(3), 765–774. https://doi.org/10.1016/s0092-8674(80)80052-3
Petes, T. D. “Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes.” Cell 19, no. 3 (March 1980): 765–74. https://doi.org/10.1016/s0092-8674(80)80052-3.
Petes TD. Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. Cell. 1980 Mar;19(3):765–74.
Petes, T. D. “Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes.” Cell, vol. 19, no. 3, Mar. 1980, pp. 765–74. Pubmed, doi:10.1016/s0092-8674(80)80052-3.
Petes TD. Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. Cell. 1980 Mar;19(3):765–774.
Published In
Cell
DOI
ISSN
0092-8674
Publication Date
March 1980
Volume
19
Issue
3
Start / End Page
765 / 774
Location
United States
Related Subject Headings
- Transformation, Genetic
- Saccharomyces cerevisiae
- Recombination, Genetic
- RNA, Ribosomal
- Plasmids
- Genes
- Developmental Biology
- DNA, Recombinant
- DNA, Fungal
- Chromosome Mapping